Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FE252_RS05300 Genome accession   NZ_CP040456
Coordinates   767901..768560 (-) Length   219 a.a.
NCBI ID   WP_112036184.1    Uniprot ID   -
Organism   Escherichia coli strain UPEC132     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 762901..773560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE252_RS05275 ygiN 763802..764116 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  FE252_RS05280 mdaB 764147..764728 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  FE252_RS27640 - 764978..765457 (+) 480 WP_000065329.1 Hcp family type VI secretion system effector -
  FE252_RS27645 - 765460..766170 (+) 711 WP_000834024.1 hypothetical protein -
  FE252_RS05290 ygiZ 766177..766509 (+) 333 WP_000914696.1 DUF2645 family protein -
  FE252_RS05295 qseC 766555..767904 (-) 1350 WP_000673388.1 quorum sensing histidine kinase QseC -
  FE252_RS05300 ciaR 767901..768560 (-) 660 WP_112036184.1 quorum sensing response regulator transcription factor QseB Regulator
  FE252_RS05305 ygiW 768712..769104 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  FE252_RS05310 ygiV 769157..769639 (+) 483 WP_000183493.1 GyrI-like domain-containing protein -
  FE252_RS05315 ygiS 769748..771355 (+) 1608 WP_001468194.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24659.57 Da        Isoelectric Point: 6.9850

>NTDB_id=321768 FE252_RS05300 WP_112036184.1 767901..768560(-) (ciaR) [Escherichia coli strain UPEC132]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEAHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=321768 FE252_RS05300 WP_112036184.1 767901..768560(-) (ciaR) [Escherichia coli strain UPEC132]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAAGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCTGTATTGATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGCGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361