Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FE252_RS03635 Genome accession   NZ_CP040456
Coordinates   447674..448306 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain UPEC132     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 442674..453306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE252_RS03610 yhfG 442806..442973 (+) 168 WP_000736859.1 YhfG family protein -
  FE252_RS03615 fic 442963..443565 (+) 603 WP_001280662.1 putative adenosine monophosphate-protein transferase Fic -
  FE252_RS03620 pabA 443597..444160 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  FE252_RS03625 argD 444246..445466 (+) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FE252_RS03630 yhfK 445533..447623 (-) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  FE252_RS03635 crp 447674..448306 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FE252_RS03640 yhfA 448608..449012 (+) 405 WP_001148908.1 OsmC family protein -
  FE252_RS03645 prkB 449067..449936 (-) 870 WP_001274680.1 phosphoribulokinase -
  FE252_RS03650 yheU 449990..450208 (-) 219 WP_000907089.1 YheU family protein -
  FE252_RS03655 yheT 450202..451224 (-) 1023 WP_000057389.1 hydrolase -
  FE252_RS03660 yheS 451224..453137 (-) 1914 WP_000634799.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=321762 FE252_RS03635 WP_000242755.1 447674..448306(-) (crp) [Escherichia coli strain UPEC132]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=321762 FE252_RS03635 WP_000242755.1 447674..448306(-) (crp) [Escherichia coli strain UPEC132]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467