Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FE252_RS01650 Genome accession   NZ_CP040456
Coordinates   28552..29142 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain UPEC132     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23552..34142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE252_RS01620 yidG 23844..24206 (+) 363 WP_001113442.1 DUF202 domain-containing protein -
  FE252_RS01625 yidF 24203..24700 (+) 498 WP_000148035.1 radical SAM protein -
  FE252_RS01630 emrD 24708..25892 (-) 1185 WP_001304999.1 multidrug efflux MFS transporter EmrD -
  FE252_RS27400 ysdE 25974..26048 (+) 75 WP_211180519.1 protein YsdE -
  FE252_RS01635 ivbL 26293..26391 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  FE252_RS01640 ilvB 26497..28185 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  FE252_RS01645 ilvN 28189..28479 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FE252_RS01650 letA 28552..29142 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FE252_RS01655 uhpB 29142..30644 (+) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FE252_RS01660 uhpC 30654..31973 (+) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FE252_RS01665 uhpT 32111..33502 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=321752 FE252_RS01650 WP_000633668.1 28552..29142(+) (letA) [Escherichia coli strain UPEC132]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=321752 FE252_RS01650 WP_000633668.1 28552..29142(+) (letA) [Escherichia coli strain UPEC132]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment