Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GALLO_RS02740 Genome accession   NC_013798
Coordinates   521672..522316 (+) Length   214 a.a.
NCBI ID   WP_009853571.1    Uniprot ID   A0A060RG88
Organism   Streptococcus gallolyticus UCN34     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 516672..527316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GALLO_RS02720 (GALLO_0493) - 517246..517983 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GALLO_RS02725 (GALLO_0494) pknB 517983..519860 (+) 1878 WP_012961536.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GALLO_RS02730 (GALLO_0495) liaF 519971..520666 (+) 696 WP_012961537.1 cell wall-active antibiotics response protein LiaF -
  GALLO_RS02735 (GALLO_0496) - 520663..521688 (+) 1026 WP_012961538.1 sensor histidine kinase -
  GALLO_RS02740 (GALLO_0497) vraR 521672..522316 (+) 645 WP_009853571.1 response regulator transcription factor Regulator
  GALLO_RS02745 (GALLO_0498) - 522435..523835 (+) 1401 WP_012961539.1 Cof-type HAD-IIB family hydrolase -
  GALLO_RS02750 (GALLO_0499) - 523835..524191 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  GALLO_RS02755 (GALLO_0500) cysK 524305..525234 (-) 930 WP_012961540.1 cysteine synthase A -
  GALLO_RS02760 (GALLO_0501) - 525338..525964 (-) 627 WP_012961541.1 YigZ family protein -
  GALLO_RS02765 (GALLO_0502) comFA/cflA 526021..527235 (+) 1215 WP_012961542.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23939.71 Da        Isoelectric Point: 4.6633

>NTDB_id=32165 GALLO_RS02740 WP_009853571.1 521672..522316(+) (vraR) [Streptococcus gallolyticus UCN34]
MTQKIKVILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=32165 GALLO_RS02740 WP_009853571.1 521672..522316(+) (vraR) [Streptococcus gallolyticus UCN34]
ATGACCCAGAAAATTAAAGTTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTTGGTGAAGCTGGAAATGGTTTAGATGGTATCAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAGGAAGCTAAA
ATTCTTGTTTTAACATCTTACCTTGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCTATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAATCAAACTATTGCTGATGAGCTATTTATCTCACTAAAAACCGTCAAAACACACGTTTCAAATAT
TTTAGCTAAGTTAGAAGTTGATGACCGTACACAAGCAGTCGTTTATGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RG88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393

Multiple sequence alignment