Detailed information NTG0320968

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: D9777_RS19625
• Genome accession: NZ_CP033054
• Coordinates: 3902330..3903493 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain Bac57
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3897330..3908493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D9777_RS19595	-	3897596..3898015 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
D9777_RS19600	comFC	3898089..3898778 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
D9777_RS19605	-	3898784..3899068 (-)	285	WP_003151389.1	competence protein ComFB	-
D9777_RS19610	-	3899126..3900510 (-)	1385	Protein_3772	DEAD/DEAH box helicase	-
D9777_RS19615	-	3900618..3901466 (-)	849	WP_003151387.1	DegV family protein	-
D9777_RS19620	degU	3901564..3902253 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
D9777_RS19625	degS	3902330..3903493 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
D9777_RS19630	-	3903716..3904363 (+)	648	WP_021494097.1	YigZ family protein	-
D9777_RS19635	-	3904368..3905582 (+)	1215	WP_014419013.1	LCP family protein	-
D9777_RS19640	-	3905672..3906748 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
D9777_RS19645	-	3906880..3908076 (-)	1197	WP_031304142.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=320968 D9777_RS19625 WP_007407484.1 3902330..3903493(-) (degS) [Bacillus velezensis strain Bac57]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=320968 D9777_RS19625 WP_007407484.1 3902330..3903493(-) (degS) [Bacillus velezensis strain Bac57]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951