Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EST53_RS01125 Genome accession   NZ_CP040269
Coordinates   218248..218904 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 1500     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 213248..223904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EST53_RS01090 (EST53_01090) dcyD 214127..215113 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  EST53_RS01095 (EST53_01095) tcyL 215128..215796 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EST53_RS01100 (EST53_01100) tcyN 215793..216545 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EST53_RS01105 (EST53_01105) sdiA 216775..217497 (+) 723 WP_089586234.1 transcriptional regulator SdiA -
  EST53_RS01110 (EST53_01110) yecF 217565..217789 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EST53_RS01115 (EST53_01115) yecU 217776..217952 (-) 177 WP_001302050.1 protein YecU -
  EST53_RS24050 (EST53_01120) - 217990..218106 (-) 117 WP_001302039.1 hypothetical protein -
  EST53_RS01125 (EST53_01125) letA 218248..218904 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EST53_RS01130 (EST53_01130) uvrC 218901..220733 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EST53_RS01135 (EST53_01135) pgsA 220790..221338 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EST53_RS01155 (EST53_01155) yecA 221987..222652 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=320885 EST53_RS01125 WP_000611335.1 218248..218904(+) (letA) [Escherichia coli strain 1500]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=320885 EST53_RS01125 WP_000611335.1 218248..218904(+) (letA) [Escherichia coli strain 1500]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment