Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EST51_RS03560 Genome accession   NZ_CP040263
Coordinates   734965..735624 (-) Length   219 a.a.
NCBI ID   WP_106106579.1    Uniprot ID   -
Organism   Escherichia coli strain 631     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 729965..740624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EST51_RS03535 (EST51_03535) parE 730056..731948 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  EST51_RS03540 (EST51_03540) ygiN 731996..732310 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  EST51_RS03545 (EST51_03545) mdaB 732341..732922 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  EST51_RS03550 (EST51_03550) ygiZ 733241..733573 (+) 333 WP_000917684.1 DUF2645 family protein -
  EST51_RS03555 (EST51_03555) qseC 733619..734968 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  EST51_RS03560 (EST51_03560) ciaR 734965..735624 (-) 660 WP_106106579.1 quorum sensing response regulator transcription factor QseB Regulator
  EST51_RS03565 (EST51_03565) ygiW 735776..736168 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  EST51_RS03570 (EST51_03570) ygiV 736221..736703 (+) 483 WP_106106578.1 GyrI-like domain-containing protein -
  EST51_RS03575 (EST51_03575) mqsR 736908..737204 (+) 297 WP_000415583.1 type II toxin-antitoxin system toxin MqsR -
  EST51_RS03580 (EST51_03580) mqsA 737206..737601 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  EST51_RS03585 (EST51_03585) ygiS 737734..739341 (+) 1608 WP_106106577.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24668.58 Da        Isoelectric Point: 6.7638

>NTDB_id=320811 EST51_RS03560 WP_106106579.1 734965..735624(-) (ciaR) [Escherichia coli strain 631]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGHQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=320811 EST51_RS03560 WP_106106579.1 734965..735624(-) (ciaR) [Escherichia coli strain 631]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCATCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365