Detailed information NTG0319928

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: D9C08_RS12725
• Genome accession: NZ_CP032872
• Coordinates: 2422114..2422893 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis subsp. subtilis strain 2KL1
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 2417114..2427893

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D9C08_RS12705 (D9C08_12705)	trmFO	2417807..2419114 (+)	1308	WP_069837510.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
D9C08_RS12710 (D9C08_12710)	xerC	2419182..2420096 (+)	915	WP_014479777.1	tyrosine recombinase XerC	-
D9C08_RS12715 (D9C08_12715)	clpQ	2420109..2420654 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
D9C08_RS12720 (D9C08_12720)	hslU	2420671..2422074 (+)	1404	WP_014476801.1	HslU--HslV peptidase ATPase subunit	-
D9C08_RS12725 (D9C08_12725)	codY	2422114..2422893 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
D9C08_RS12730 (D9C08_12730)	flgB	2423273..2423662 (+)	390	WP_014479778.1	flagellar basal body rod protein FlgB	-
D9C08_RS12735 (D9C08_12735)	flgC	2423662..2424114 (+)	453	WP_014479779.1	flagellar basal body rod protein FlgC	-
D9C08_RS12740 (D9C08_12740)	fliE	2424125..2424445 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
D9C08_RS12745 (D9C08_12745)	fliF	2424491..2426101 (+)	1611	WP_046160402.1	flagellar basal-body MS-ring/collar protein FliF	-
D9C08_RS12750 (D9C08_12750)	fliG	2426114..2427130 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
D9C08_RS12755 (D9C08_12755)	fliH	2427123..2427875 (+)	753	WP_014479782.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=319928 D9C08_RS12725 WP_003220850.1 2422114..2422893(+) (codY) [Bacillus subtilis subsp. subtilis strain 2KL1]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=319928 D9C08_RS12725 WP_003220850.1 2422114..2422893(+) (codY) [Bacillus subtilis subsp. subtilis strain 2KL1]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCTATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCTTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467