Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   D7A46_RS06270 Genome accession   NZ_CP032743
Coordinates   1178573..1179238 (+) Length   221 a.a.
NCBI ID   WP_000203219.1    Uniprot ID   A0A219CAS9
Organism   Acinetobacter baumannii strain C25     
Function   regulate competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1179295..1190606 1178573..1179238 flank 57


Gene organization within MGE regions


Location: 1178573..1190606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7A46_RS06270 (D7A46_06265) crp 1178573..1179238 (+) 666 WP_000203219.1 cAMP-activated global transcriptional regulator CRP Regulator
  D7A46_RS06275 (D7A46_06270) - 1179295..1180385 (+) 1091 WP_085940413.1 IS4-like element ISAba1 family transposase -
  D7A46_RS06280 (D7A46_06275) - 1180630..1181244 (+) 615 Protein_1132 aldo/keto reductase -
  D7A46_RS06285 (D7A46_06280) - 1181289..1181993 (+) 705 WP_001067855.1 IS6-like element IS26 family transposase -
  D7A46_RS06295 (D7A46_06290) - 1182033..1182473 (+) 441 WP_014839977.1 TetR/AcrR family transcriptional regulator -
  D7A46_RS06300 (D7A46_06295) - 1182493..1183281 (+) 789 WP_014839978.1 transcriptional regulator -
  D7A46_RS06305 (D7A46_06300) - 1183281..1183799 (+) 519 WP_014839979.1 FidL-like protein -
  D7A46_RS06310 (D7A46_06305) - 1183804..1184220 (-) 417 WP_014839980.1 fosfomycin resistance glutathione transferase FosA3 -
  D7A46_RS06315 (D7A46_06310) - 1184606..1185310 (+) 705 WP_001067855.1 IS6-like element IS26 family transposase -
  D7A46_RS06320 (D7A46_06315) bla 1185360..1186103 (+) 744 Protein_1139 class A beta-lactamase -
  D7A46_RS06325 (D7A46_06320) - 1186361..1186837 (+) 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
  D7A46_RS06330 (D7A46_06325) - 1186884..1187759 (-) 876 WP_015387340.1 extended-spectrum class A beta-lactamase CTX-M-55 -
  D7A46_RS06335 (D7A46_06330) - 1188181..1188885 (-) 705 WP_001067858.1 IS6-like element IS26 family transposase -
  D7A46_RS06340 (D7A46_06335) intI1 1188950..1189630 (-) 681 Protein_1143 class 1 integron integrase IntI1 -
  D7A46_RS06345 (D7A46_06340) - 1189902..1190606 (+) 705 WP_001067855.1 IS6-like element IS26 family transposase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24956.78 Da        Isoelectric Point: 8.1128

>NTDB_id=318439 D7A46_RS06270 WP_000203219.1 1178573..1179238(+) (crp) [Acinetobacter baumannii strain C25]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFLCTR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=318439 D7A46_RS06270 WP_000203219.1 1178573..1179238(+) (crp) [Acinetobacter baumannii strain C25]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCGGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGCCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTCTCTGTACACGATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, crp family (Crp)

(176-207)

Cyclic nucleotide-binding domain (cNMP_binding)

(33-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A219CAS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Acinetobacter baumannii D1279779

100

98.19

0.982
  crp Vibrio cholerae strain A1552

47.317

92.76

0.439
  crp Haemophilus influenzae Rd KW20

48.705

87.33

0.425

Multiple sequence alignment