Detailed information NTG0318334

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: D8S77_RS07145
• Genome accession: NZ_CP032700
• Coordinates: 1409803..1410804 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY556
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1404803..1415804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S77_RS07130 (D8S77_07135)	thrS	1404973..1406916 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
D8S77_RS07135 (D8S77_07140)	-	1407338..1408672 (-)	1335	WP_032460075.1	glycosyltransferase family 4 protein	-
D8S77_RS07140 (D8S77_07145)	-	1408674..1409672 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
D8S77_RS07145 (D8S77_07150)	ccpA	1409803..1410804 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
D8S77_RS07150 (D8S77_07155)	-	1410978..1412063 (+)	1086	WP_129322128.1	aminopeptidase P family protein	-
D8S77_RS07155 (D8S77_07160)	-	1412112..1412777 (+)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
D8S77_RS07160 (D8S77_07165)	-	1412788..1413165 (+)	378	WP_002985686.1	VOC family protein	-
D8S77_RS07165 (D8S77_07170)	-	1413310..1414236 (+)	927	WP_111689635.1	glycosyltransferase family 2 protein	-
D8S77_RS07170 (D8S77_07175)	-	1414447..1415130 (+)	684	WP_111689636.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=318334 D8S77_RS07145 WP_002985680.1 1409803..1410804(-) (ccpA) [Streptococcus pyogenes strain TSPY556]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=318334 D8S77_RS07145 WP_002985680.1 1409803..1410804(-) (ccpA) [Streptococcus pyogenes strain TSPY556]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559