Detailed information NTG0318261

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: D8S76_RS02390
• Genome accession: NZ_CP032699
• Coordinates: 427433..428434 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY155
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 422433..433434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S76_RS02365 (D8S76_02360)	-	423107..423790 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
D8S76_RS02370 (D8S76_02365)	-	424001..424927 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
D8S76_RS02375 (D8S76_02370)	-	425072..425449 (-)	378	WP_115224547.1	VOC family protein	-
D8S76_RS02380 (D8S76_02375)	-	425460..426125 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
D8S76_RS02385 (D8S76_02380)	-	426174..427259 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
D8S76_RS02390 (D8S76_02385)	ccpA	427433..428434 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
D8S76_RS02395 (D8S76_02390)	-	428565..429563 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
D8S76_RS02400 (D8S76_02395)	-	429565..430899 (+)	1335	WP_115224548.1	glycosyltransferase family 4 protein	-
D8S76_RS02405 (D8S76_02400)	thrS	431321..433264 (+)	1944	WP_111677101.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=318261 D8S76_RS02390 WP_002985680.1 427433..428434(+) (ccpA) [Streptococcus pyogenes strain TSPY155]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=318261 D8S76_RS02390 WP_002985680.1 427433..428434(+) (ccpA) [Streptococcus pyogenes strain TSPY155]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559