Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FCV42_RS03945 Genome accession   NZ_CP039834
Coordinates   809410..810069 (-) Length   219 a.a.
NCBI ID   WP_021500303.1    Uniprot ID   -
Organism   Escherichia coli O157:H7 strain MB41-1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 804410..815069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FCV42_RS03920 (FCV42_04000) - 805152..806099 (+) 948 WP_001301797.1 iron-siderophore ABC transporter substrate-binding protein -
  FCV42_RS03925 (FCV42_04005) - 806096..806983 (+) 888 WP_000614950.1 MurR/RpiR family transcriptional regulator -
  FCV42_RS03930 (FCV42_04010) ygiN 807028..807342 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  FCV42_RS03935 (FCV42_04015) mdaB 807373..807954 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  FCV42_RS03940 (FCV42_04020) qseC 808064..809413 (-) 1350 WP_000673362.1 quorum sensing histidine kinase QseC -
  FCV42_RS03945 (FCV42_04025) ciaR 809410..810069 (-) 660 WP_021500303.1 quorum sensing response regulator transcription factor QseB Regulator
  FCV42_RS03950 (FCV42_04030) ygiW 810221..810613 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  FCV42_RS03955 (FCV42_04035) ygiV 810666..811148 (+) 483 WP_000183479.1 GyrI-like domain-containing protein -
  FCV42_RS03960 (FCV42_04040) ygiS 811257..812864 (+) 1608 WP_001301989.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24803.70 Da        Isoelectric Point: 6.3558

>NTDB_id=318220 FCV42_RS03945 WP_021500303.1 809410..810069(-) (ciaR) [Escherichia coli O157:H7 strain MB41-1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLDEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=318220 FCV42_RS03945 WP_021500303.1 809410..810069(-) (ciaR) [Escherichia coli O157:H7 strain MB41-1]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGATGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment