Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   FA954_RS02225 Genome accession   NZ_CP039710
Coordinates   421688..423667 (+) Length   659 a.a.
NCBI ID   WP_037997783.1    Uniprot ID   A0ABS0QG24
Organism   Thermoactinomyces vulgaris strain 2H     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 416688..428667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FA954_RS02210 (FA954_02210) - 417680..418762 (+) 1083 WP_049720671.1 M23 family metallopeptidase -
  FA954_RS02215 (FA954_02215) - 418888..420339 (+) 1452 WP_037997778.1 S41 family peptidase -
  FA954_RS02220 (FA954_02220) - 420397..421536 (+) 1140 WP_165489724.1 PDZ domain-containing protein -
  FA954_RS02225 (FA954_02225) uvrB 421688..423667 (+) 1980 WP_037997783.1 excinuclease ABC subunit UvrB Machinery gene
  FA954_RS02230 (FA954_02230) uvrA 423671..426550 (+) 2880 WP_138614829.1 excinuclease ABC subunit UvrA Machinery gene
  FA954_RS02235 (FA954_02235) - 426634..426843 (+) 210 WP_037997788.1 alpha/beta-type small acid-soluble spore protein -
  FA954_RS02240 (FA954_02240) - 426858..427091 (-) 234 WP_138614830.1 DUF2553 family protein -
  FA954_RS02245 (FA954_02245) - 427386..427796 (+) 411 WP_049720669.1 DUF302 domain-containing protein -
  FA954_RS02250 (FA954_02250) - 428009..428344 (+) 336 WP_037993291.1 phage holin family protein -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 75732.67 Da        Isoelectric Point: 5.8221

>NTDB_id=318151 FA954_RS02225 WP_037997783.1 421688..423667(+) (uvrB) [Thermoactinomyces vulgaris strain 2H]
MGKQFQLVSDFEPRGDQPQAIEKLVRQIQAGNKYQTLLGATGTGKTFTMAQTIARVNKPTLVIAHNKTLAAQLCGELKEF
FPHNAVEYFVSYYDYYQPEAYIPATDTYIEKDASINDEIDKLRHSATSALFEREDVIIVSSVSCIYGLGSPTEYRDLVLS
LRVGMERDRNEVLRKLVDIQYERNDINFVRGTFRVRGDVVEIFPASRSEQAVRVEFFGDEIDRIREIDVVTGEIIGEREH
VAIFPASHYVTRSDVMERALKGIEQELDERLKELREQGKLLEAQRLEQRTRYDLEMMREVGFCSGIENYSRHLVGKKPGE
PPYTLLDFFPKDFLIIVDESHVTIPQIHGMYNGDQARKEMLVEHGFRLPSAKDNRPLRFSEFEEKINQILFVSATPGPYE
LEKSPEVVEQIIRPTGLLDPKIHIHPIKGQIDHLIGLIHDRIEQDERVLVTTLTKKMAEDLTDYLKEMGIKVRYLHSDIK
TIERMKILRDLRLGEFDVLIGINLLREGLDLPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAHGEVVMYADKITDSM
KKAIDETERRRQIQAAYNKKHGIVPQTIQKDVREVIEATKVAEQTAEYVTGKQTKKMSKSERNKLIRDLEKEMKEAAKEL
NFERAAELRDLIIELKAEV

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=318151 FA954_RS02225 WP_037997783.1 421688..423667(+) (uvrB) [Thermoactinomyces vulgaris strain 2H]
ATGGGAAAACAATTCCAACTGGTGTCGGATTTTGAGCCGCGTGGGGATCAACCGCAGGCGATTGAGAAACTGGTCCGCCA
AATTCAGGCGGGCAACAAGTACCAAACCCTTTTGGGAGCCACGGGGACGGGGAAAACGTTTACCATGGCCCAAACGATTG
CCCGGGTCAACAAACCCACGCTGGTGATTGCGCACAACAAGACGTTGGCGGCGCAGTTGTGCGGGGAGTTGAAGGAATTC
TTCCCCCATAATGCCGTCGAATATTTTGTCAGTTATTATGATTATTATCAACCTGAAGCTTATATTCCGGCAACGGATAC
TTATATAGAAAAAGATGCGTCCATCAATGATGAAATTGACAAGTTGCGCCACTCGGCAACCAGCGCTCTGTTTGAGCGGG
AAGATGTGATTATTGTTTCGAGTGTTTCTTGTATTTACGGCTTGGGTTCACCGACGGAATACCGGGATCTGGTTCTTTCC
TTGCGAGTGGGAATGGAAAGGGACCGGAACGAAGTGTTGCGTAAGTTGGTGGATATCCAATATGAACGAAACGATATCAA
TTTTGTGCGCGGAACGTTCCGGGTGCGGGGCGATGTGGTGGAGATTTTCCCTGCTTCCCGGAGTGAACAAGCGGTCCGGG
TGGAGTTTTTTGGGGATGAGATTGACCGGATTCGCGAAATTGATGTCGTGACGGGAGAAATTATCGGGGAAAGGGAACAT
GTTGCCATCTTCCCGGCTTCTCACTATGTCACCCGTTCCGATGTGATGGAAAGGGCTTTGAAAGGGATTGAACAGGAGCT
GGATGAACGGCTCAAGGAACTGAGGGAACAAGGCAAACTGCTGGAAGCACAACGCTTGGAGCAAAGGACGAGATATGATT
TGGAAATGATGCGGGAAGTCGGATTTTGTTCCGGGATCGAGAACTATTCCCGCCACCTGGTCGGCAAAAAGCCGGGAGAA
CCGCCTTACACCTTGTTGGACTTTTTCCCGAAAGACTTCTTGATCATAGTGGATGAGTCCCATGTCACCATTCCGCAAAT
TCACGGGATGTACAACGGGGATCAGGCGCGAAAGGAGATGTTGGTGGAGCACGGTTTCCGGCTTCCGTCGGCCAAAGACA
ACCGGCCGCTCAGATTTAGCGAGTTTGAAGAAAAGATTAATCAGATCTTATTTGTTTCCGCGACACCGGGTCCGTATGAA
TTGGAGAAATCGCCGGAAGTGGTGGAACAGATTATCCGCCCGACAGGGTTGTTGGATCCGAAAATCCATATCCATCCGAT
CAAGGGGCAAATTGACCACCTGATCGGGCTGATTCATGACCGCATTGAACAGGATGAACGCGTGCTGGTGACGACCCTGA
CGAAAAAAATGGCGGAGGATTTGACGGATTATCTGAAAGAAATGGGGATCAAAGTCCGCTATTTGCATTCGGATATCAAA
ACCATTGAACGGATGAAAATCTTACGCGATCTGCGTCTGGGTGAATTTGACGTGTTGATTGGGATTAACCTGTTAAGGGA
AGGATTGGATTTACCGGAAGTTTCCCTGGTGGCGATTTTGGATGCCGACAAAGAAGGATTTTTGCGTTCGGAGCGTTCTT
TGATCCAAACCATCGGACGGGCTGCGCGGAATGCCCACGGAGAAGTGGTGATGTATGCGGACAAGATCACCGACTCCATG
AAAAAAGCGATCGATGAAACAGAGCGCCGTCGGCAAATTCAAGCGGCCTACAATAAAAAACACGGAATTGTCCCCCAAAC
GATTCAAAAAGACGTGCGTGAAGTGATTGAGGCGACCAAAGTGGCGGAACAAACCGCTGAATATGTGACAGGAAAACAAA
CGAAGAAAATGAGCAAGTCTGAACGGAACAAGTTGATCCGCGACCTGGAAAAAGAAATGAAAGAAGCCGCCAAAGAGTTG
AATTTTGAACGTGCTGCCGAATTGCGGGATTTGATTATCGAATTGAAAGCGGAGGTTTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(11-139)

Ultra-violet resistance protein B (UvrB)

(551-593)

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(624-657)

Helicase conserved C-terminal domain (Helicase_C)

(431-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

68.14

99.545

0.678
  uvrB Streptococcus pneumoniae R6

67.988

99.545

0.677
  uvrB Streptococcus pneumoniae D39

67.988

99.545

0.677