Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E9097_RS24560 Genome accession   NZ_CP039404
Coordinates   4877562..4878152 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 377323_2f     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4872562..4883152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E9097_RS24545 (E9097_24545) uhpT 4873202..4874593 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  E9097_RS24550 (E9097_24550) uhpC 4874731..4876050 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  E9097_RS24555 (E9097_24555) uhpB 4876060..4877562 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  E9097_RS24560 (E9097_24560) letA 4877562..4878152 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  E9097_RS24565 (E9097_24565) ilvN 4878225..4878515 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  E9097_RS24570 (E9097_24570) ilvB 4878519..4880207 (-) 1689 WP_000168500.1 acetolactate synthase large subunit -
  E9097_RS24575 (E9097_24575) ivbL 4880313..4880411 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  E9097_RS25600 ysdE 4880656..4880730 (-) 75 WP_211180519.1 protein YsdE -
  E9097_RS24580 (E9097_24580) emrD 4880812..4881996 (+) 1185 WP_001304999.1 multidrug efflux MFS transporter EmrD -
  E9097_RS24585 (E9097_24585) yidF 4882004..4882501 (-) 498 WP_000148034.1 radical SAM protein -
  E9097_RS24590 (E9097_24590) yidG 4882498..4882860 (-) 363 WP_001113432.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=317676 E9097_RS24560 WP_000633668.1 4877562..4878152(-) (letA) [Escherichia coli strain 377323_2f]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=317676 E9097_RS24560 WP_000633668.1 4877562..4878152(-) (letA) [Escherichia coli strain 377323_2f]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378