Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   E9097_RS22555 Genome accession   NZ_CP039404
Coordinates   4463179..4463811 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 377323_2f     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4458179..4468811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E9097_RS22530 (E9097_22530) yheS 4458348..4460261 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  E9097_RS22535 (E9097_22535) yheT 4460261..4461283 (+) 1023 WP_136503182.1 hydrolase -
  E9097_RS22540 (E9097_22540) yheU 4461277..4461495 (+) 219 WP_000907085.1 YheU family protein -
  E9097_RS22545 (E9097_22545) prkB 4461549..4462418 (+) 870 WP_001274684.1 phosphoribulokinase -
  E9097_RS22550 (E9097_22550) yhfA 4462473..4462877 (-) 405 WP_001148908.1 OsmC family protein -
  E9097_RS22555 (E9097_22555) crp 4463179..4463811 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  E9097_RS22560 (E9097_22560) yhfK 4463862..4465952 (+) 2091 WP_032343928.1 YccS/YhfK family putative transporter -
  E9097_RS22565 (E9097_22565) argD 4466030..4467250 (-) 1221 WP_021560063.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  E9097_RS22570 (E9097_22570) pabA 4467336..4467899 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  E9097_RS22575 (E9097_22575) fic 4467931..4468533 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  E9097_RS22580 (E9097_22580) yhfG 4468523..4468690 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=317669 E9097_RS22555 WP_000242755.1 4463179..4463811(+) (crp) [Escherichia coli strain 377323_2f]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=317669 E9097_RS22555 WP_000242755.1 4463179..4463811(+) (crp) [Escherichia coli strain 377323_2f]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467