Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E7Z58_RS15010 Genome accession   NZ_CP039298
Coordinates   3016688..3017278 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain PigCaeca_1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3011688..3022278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E7Z58_RS14980 (E7Z58_14970) yidF 3011803..3012300 (+) 498 WP_000148061.1 radical SAM protein -
  E7Z58_RS14985 (E7Z58_14975) emrD 3012308..3013492 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  E7Z58_RS24600 ysdE 3013574..3013648 (+) 75 WP_211180519.1 protein YsdE -
  E7Z58_RS14990 (E7Z58_14980) tisB 3013772..3013861 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  E7Z58_RS14995 (E7Z58_14985) ivbL 3014426..3014524 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  E7Z58_RS15000 (E7Z58_14990) ilvB 3014630..3016318 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  E7Z58_RS15005 (E7Z58_14995) ilvN 3016322..3016612 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  E7Z58_RS15010 (E7Z58_15000) letA 3016688..3017278 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  E7Z58_RS15015 (E7Z58_15005) uhpB 3017278..3018780 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  E7Z58_RS15020 (E7Z58_15010) uhpC 3018790..3020109 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  E7Z58_RS15025 (E7Z58_15015) uhpT 3020247..3021638 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=317271 E7Z58_RS15010 WP_000633668.1 3016688..3017278(+) (letA) [Escherichia coli strain PigCaeca_1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=317271 E7Z58_RS15010 WP_000633668.1 3016688..3017278(+) (letA) [Escherichia coli strain PigCaeca_1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378