Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   E1950_RS08490 Genome accession   NZ_CP039162
Coordinates   1710059..1711048 (-) Length   329 a.a.
NCBI ID   WP_000219066.1    Uniprot ID   P67655
Organism   Staphylococcus aureus strain Lr12     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705059..1716048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1950_RS08475 (E1950_08655) acsA 1706260..1707966 (-) 1707 WP_103152291.1 acetate--CoA ligase -
  E1950_RS08480 (E1950_08660) - 1708135..1708767 (+) 633 WP_001016004.1 hypothetical protein -
  E1950_RS08485 (E1950_08665) - 1708792..1709961 (+) 1170 WP_103152292.1 acetoin utilization protein AcuC -
  E1950_RS08490 (E1950_08670) ccpA 1710059..1711048 (-) 990 WP_000219066.1 catabolite control protein A Regulator
  E1950_RS08495 (E1950_08675) - 1711121..1711234 (-) 114 WP_138118348.1 hypothetical protein -
  E1950_RS08500 (E1950_08680) - 1711588..1712679 (-) 1092 WP_000066378.1 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase -
  E1950_RS08505 (E1950_08685) - 1713134..1713217 (-) 84 WP_031761406.1 hypothetical protein -
  E1950_RS08510 (E1950_08690) - 1713373..1714731 (-) 1359 WP_000193903.1 hypothetical protein -
  E1950_RS08515 (E1950_08695) - 1714805..1715296 (-) 492 WP_000383814.1 DUF948 domain-containing protein -

Sequence

Protein


Download         Length: 329 a.a.        Molecular weight: 36060.24 Da        Isoelectric Point: 5.5054

>NTDB_id=317096 E1950_RS08490 WP_000219066.1 1710059..1711048(-) (ccpA) [Staphylococcus aureus strain Lr12]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide


Download         Length: 990 bp        

>NTDB_id=317096 E1950_RS08490 WP_000219066.1 1710059..1711048(-) (ccpA) [Staphylococcus aureus strain Lr12]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCTAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(4-49)

Periplasmic binding protein-like domain (Peripla_BP_3)

(171-328)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P67655

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

47.879

100

0.48
  ccpA Streptococcus gordonii str. Challis substr. CH1

47.112

100

0.471
  ccpA Streptococcus pneumoniae D39

46.201

100

0.462