Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E5N77_RS19140 Genome accession   NZ_CP039123
Coordinates   4222903..4223577 (+) Length   224 a.a.
NCBI ID   WP_019324931.1    Uniprot ID   A0ABW1XYX7
Organism   Streptomyces sp. SS52     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4217903..4228577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5N77_RS19120 (E5N77_19120) - 4217958..4219235 (+) 1278 WP_239471352.1 acyltransferase -
  E5N77_RS19125 (E5N77_19125) - 4219228..4220619 (+) 1392 WP_239099589.1 sensor histidine kinase -
  E5N77_RS19130 (E5N77_19130) vraR 4220616..4221299 (+) 684 WP_019324929.1 response regulator transcription factor Regulator
  E5N77_RS19135 (E5N77_19135) - 4221557..4222906 (+) 1350 WP_239471353.1 histidine kinase -
  E5N77_RS19140 (E5N77_19140) vraR 4222903..4223577 (+) 675 WP_019324931.1 response regulator transcription factor Regulator
  E5N77_RS19145 (E5N77_19145) - 4223701..4224912 (+) 1212 WP_127435816.1 cytochrome P450 -
  E5N77_RS19150 (E5N77_19150) - 4224956..4226623 (-) 1668 WP_136235881.1 ABC transporter permease -
  E5N77_RS19155 (E5N77_19155) - 4226620..4227594 (-) 975 WP_136235882.1 ABC transporter ATP-binding protein -
  E5N77_RS19160 (E5N77_19160) - 4227668..4228174 (+) 507 WP_019324935.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24173.95 Da        Isoelectric Point: 4.7385

>NTDB_id=316802 E5N77_RS19140 WP_019324931.1 4222903..4223577(+) (vraR) [Streptomyces sp. SS52]
MTDRTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVAKVRELGPDVVLMDIRMPELNGIEATREIVAADGTA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSITRRLITEFSKLSDGPRLMPQAQAAYGD
LTERETEVLVLIAQGLSNAEIAGRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=316802 E5N77_RS19140 WP_019324931.1 4222903..4223577(+) (vraR) [Streptomyces sp. SS52]
ATGACCGACCGCACGATCCGCGTACTGATCGCCGACGACCAGATGATGGTGCGTGAGGGCTTCTCGGTGCTGCTCAACGC
GATGCCGGACATCGAGGTCGTCGGTGAGGCGGTCAACGGCCGGGAGGCCGTGGCCAAGGTCCGCGAACTCGGCCCGGACG
TCGTCCTGATGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTCGCCGCCGACGGGACGGCG
AAGGTGCTCGTCCTCACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCGGGCGCCTCCGGCTTCCTGCT
CAAGGACGCCTCGGCCCGGCAGCTCGCCGACGGCGTCCGGGTGGTGGCCGCCGGTGAGGCCCTGCTCGCCCCCTCGATCA
CCCGACGTCTGATCACCGAGTTCTCGAAGCTGTCCGACGGCCCGCGTCTGATGCCCCAGGCGCAGGCGGCCTACGGGGAT
CTGACCGAGCGGGAGACGGAGGTGCTGGTGCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGGGCGCCTGGTGGT
CGCCGAGTCGACGATCAAGACCCACGTCAGTCGCATCCTGGTGAAGCTCGGCCTGCGCGACCGCACGCAGGCGGCGGTGT
TCGCGTACGAGGCGCGGCTGGTGACGCCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-117)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.24

96.875

0.429
  degU Bacillus subtilis subsp. subtilis str. 168

41.935

96.875

0.406