Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E5N77_RS19130 Genome accession   NZ_CP039123
Coordinates   4220616..4221299 (+) Length   227 a.a.
NCBI ID   WP_019324929.1    Uniprot ID   A0ABW1Y1W4
Organism   Streptomyces sp. SS52     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4215616..4226299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5N77_RS19110 (E5N77_19110) - 4215711..4216667 (+) 957 WP_136235880.1 alpha/beta hydrolase fold domain-containing protein -
  E5N77_RS19115 (E5N77_19115) - 4216976..4217965 (+) 990 WP_046249513.1 alpha/beta hydrolase -
  E5N77_RS19120 (E5N77_19120) - 4217958..4219235 (+) 1278 WP_239471352.1 acyltransferase -
  E5N77_RS19125 (E5N77_19125) - 4219228..4220619 (+) 1392 WP_239099589.1 sensor histidine kinase -
  E5N77_RS19130 (E5N77_19130) vraR 4220616..4221299 (+) 684 WP_019324929.1 response regulator transcription factor Regulator
  E5N77_RS19135 (E5N77_19135) - 4221557..4222906 (+) 1350 WP_239471353.1 histidine kinase -
  E5N77_RS19140 (E5N77_19140) vraR 4222903..4223577 (+) 675 WP_019324931.1 response regulator transcription factor Regulator
  E5N77_RS19145 (E5N77_19145) - 4223701..4224912 (+) 1212 WP_127435816.1 cytochrome P450 -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24429.12 Da        Isoelectric Point: 4.7259

>NTDB_id=316801 E5N77_RS19130 WP_019324929.1 4220616..4221299(+) (vraR) [Streptomyces sp. SS52]
MTSGSPGVIRVVIADDQQMVRQGFTVLLNTQSDIEVIGQAVDGLDAVSKVAELSPDVVLMDIRMPELGGIEATRRIVGAS
PDIRVLVLTTFDLDEYVYEALVAGASGFLLKDASADQLAEAVRVVAAGDALLAPGVTRRLITEFSRMRDRPRTPLKERVG
DLTERETEVLALIAQGLSNAEIAGRLVVAEQTVKTHVGRILVKLGLRDRTQAAVYAYECGLVRPSGY

Nucleotide


Download         Length: 684 bp        

>NTDB_id=316801 E5N77_RS19130 WP_019324929.1 4220616..4221299(+) (vraR) [Streptomyces sp. SS52]
ATGACGAGCGGCAGCCCCGGTGTGATCCGCGTGGTGATCGCCGACGACCAGCAGATGGTCCGGCAGGGATTCACCGTGCT
GCTCAACACCCAGTCCGACATCGAGGTGATCGGGCAGGCGGTGGACGGCCTGGACGCGGTGTCCAAGGTCGCCGAACTCT
CCCCGGACGTGGTCCTCATGGACATCCGCATGCCGGAGCTGGGCGGGATCGAGGCCACCCGCCGCATCGTCGGGGCGAGC
CCGGACATCAGGGTGCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACGAGGCGCTGGTCGCCGGTGCCTCCGG
GTTCCTGCTCAAGGACGCCTCCGCCGACCAACTCGCCGAGGCGGTCCGGGTGGTGGCGGCCGGGGACGCGCTGCTGGCCC
CCGGGGTGACCCGGCGGTTGATCACCGAGTTCTCCCGGATGCGGGACAGACCGCGCACCCCGCTGAAGGAACGCGTCGGC
GACCTGACCGAGCGGGAGACGGAGGTGCTCGCCCTGATCGCCCAGGGGCTGTCGAACGCGGAGATCGCCGGGCGCCTGGT
GGTCGCCGAGCAGACGGTGAAGACCCACGTGGGCCGCATCCTGGTGAAGCTCGGCCTGCGCGACCGCACGCAGGCGGCGG
TGTACGCGTACGAGTGCGGTCTGGTCCGCCCGTCGGGTTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-123)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.116

94.714

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

40.807

98.238

0.401