Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   D6869_RS04635 Genome accession   NZ_CP032526
Coordinates   875797..877269 (+) Length   490 a.a.
NCBI ID   WP_041931273.1    Uniprot ID   -
Organism   Lactococcus cremoris strain 4B0     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 870797..882269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D6869_RS04605 (D6869_04665) - 871273..872109 (+) 837 WP_011834858.1 metallophosphoesterase -
  D6869_RS04610 (D6869_04670) - 872202..873113 (+) 912 WP_011676635.1 CHAP domain-containing protein -
  D6869_RS04615 (D6869_04675) - 873350..873712 (+) 363 WP_011834859.1 TIGR02328 family protein -
  D6869_RS04620 (D6869_04680) - 874036..874281 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  D6869_RS04625 (D6869_04685) - 874414..874944 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  D6869_RS04630 (D6869_04690) covR 875100..875792 (+) 693 WP_011834861.1 response regulator transcription factor Regulator
  D6869_RS04635 (D6869_04695) covS 875797..877269 (+) 1473 WP_041931273.1 HAMP domain-containing histidine kinase Regulator
  D6869_RS04640 (D6869_04700) - 877455..878696 (+) 1242 WP_014734987.1 ammonium transporter -
  D6869_RS04645 (D6869_04705) - 878778..879119 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  D6869_RS04650 (D6869_04710) murD 879288..880637 (+) 1350 WP_011834864.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  D6869_RS04655 (D6869_04715) murG 880880..881953 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55862.69 Da        Isoelectric Point: 4.7011

>NTDB_id=316713 D6869_RS04635 WP_041931273.1 875797..877269(+) (covS) [Lactococcus cremoris strain 4B0]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSAEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=316713 D6869_RS04635 WP_041931273.1 875797..877269(+) (covS) [Lactococcus cremoris strain 4B0]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGCTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGATCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTAGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGTAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTGCTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment