Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A13_RS19575 Genome accession   NZ_CP038859
Coordinates   4063823..4064413 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 357900     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4058823..4069413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A13_RS19560 (A7A13_19920) uhpT 4059463..4060854 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  A7A13_RS19565 (A7A13_19925) uhpC 4060992..4062311 (-) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  A7A13_RS19570 (A7A13_19930) uhpB 4062321..4063823 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  A7A13_RS19575 (A7A13_19935) letA 4063823..4064413 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  A7A13_RS19580 (A7A13_19940) ilvN 4064488..4064778 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  A7A13_RS19585 (A7A13_19945) ilvB 4064782..4066470 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  A7A13_RS19590 (A7A13_19950) ivbL 4066576..4066674 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  A7A13_RS19595 (A7A13_19955) tisB 4067239..4067328 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  A7A13_RS23460 ysdE 4067591..4067665 (-) 75 WP_211180519.1 protein YsdE -
  A7A13_RS19600 (A7A13_19960) emrD 4067747..4068931 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=316360 A7A13_RS19575 WP_000633668.1 4063823..4064413(-) (letA) [Escherichia coli strain 357900]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=316360 A7A13_RS19575 WP_000633668.1 4063823..4064413(-) (letA) [Escherichia coli strain 357900]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment