Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   TFGB2_RS12500 Genome accession   NZ_CP032429
Coordinates   2106500..2107753 (+) Length   417 a.a.
NCBI ID   WP_003696286.1    Uniprot ID   A0AB74ETB0
Organism   Neisseria gonorrhoeae strain TFG-B2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2101500..2112753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TFGB2_RS12480 (TFGB2_02197) - 2102250..2103251 (+) 1002 WP_010356039.1 thiamine ABC transporter substrate-binding protein -
  TFGB2_RS12485 (TFGB2_02198) - 2103345..2104193 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  TFGB2_RS12490 (TFGB2_02199) - 2104220..2104702 (+) 483 WP_003694396.1 CinA family protein -
  TFGB2_RS12495 (TFGB2_02200) msrAB 2104786..2106354 (-) 1569 WP_003687002.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  TFGB2_RS12500 (TFGB2_02201) pilA 2106500..2107753 (+) 1254 WP_003696286.1 signal recognition particle-docking protein FtsY Machinery gene
  TFGB2_RS13520 - 2107830..2108003 (-) 174 WP_169300794.1 hypothetical protein -
  TFGB2_RS12505 (TFGB2_02202) - 2108017..2108696 (-) 680 Protein_2141 opacity family porin -
  TFGB2_RS12515 (TFGB2_02203) pilE 2109296..2109805 (-) 510 WP_134797946.1 pilin Machinery gene
  TFGB2_RS12520 - 2110174..2110317 (-) 144 WP_003691943.1 hypothetical protein -
  TFGB2_RS14195 - 2110620..2110723 (-) 104 Protein_2144 pilin -
  TFGB2_RS12535 (TFGB2_02204) pilE 2110861..2111292 (-) 432 WP_050170900.1 pilin Machinery gene
  TFGB2_RS12540 (TFGB2_02205) lpxC 2111399..2112322 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44331.70 Da        Isoelectric Point: 4.8647

>NTDB_id=315794 TFGB2_RS12500 WP_003696286.1 2106500..2107753(+) (pilA) [Neisseria gonorrhoeae strain TFG-B2]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=315794 TFGB2_RS12500 WP_003696286.1 2106500..2107753(+) (pilA) [Neisseria gonorrhoeae strain TFG-B2]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGGCCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCGGGCGATACCTTCCGCGCCGCCGCCCGTGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CCAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

100

100

1

Multiple sequence alignment