Detailed information NTG0315706

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: D3880_RS14115
• Genome accession: NZ_CP032419
• Coordinates: 3098057..3100282 (-)
• Length: 741 a.a.
• NCBI ID: WP_119894076.1
• Uniprot ID: A0A385Z3Y8
• Organism: Pseudomonas cavernae strain K2W31S-8
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3093057..3105282

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D3880_RS14080 (D3880_14085)	murB	3093466..3094485 (-)	1020	WP_119894069.1	UDP-N-acetylmuramate dehydrogenase	-
D3880_RS14085 (D3880_14090)	-	3094482..3094946 (-)	465	WP_119894070.1	low molecular weight protein-tyrosine-phosphatase	-
D3880_RS14090 (D3880_14095)	kdsB	3094946..3095710 (-)	765	WP_119894071.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
D3880_RS14095 (D3880_14100)	-	3095707..3095892 (-)	186	WP_119894072.1	Trm112 family protein	-
D3880_RS14100 (D3880_14105)	lpxK	3095909..3096913 (-)	1005	WP_119894073.1	tetraacyldisaccharide 4'-kinase	-
D3880_RS14105 (D3880_14110)	-	3096913..3097353 (-)	441	WP_119894074.1	ExbD/TolR family protein	-
D3880_RS14110 (D3880_14115)	exbB	3097350..3097985 (-)	636	WP_119894075.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
D3880_RS14115 (D3880_14120)	comA	3098057..3100282 (-)	2226	WP_119894076.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
D3880_RS14120 (D3880_14125)	-	3100425..3100985 (+)	561	WP_119894077.1	DUF2062 domain-containing protein	-
D3880_RS14125 (D3880_14130)	-	3101025..3102269 (-)	1245	WP_119894078.1	lipoprotein-releasing ABC transporter permease subunit	-
D3880_RS14130 (D3880_14135)	lolD	3102269..3102952 (-)	684	WP_119894079.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
D3880_RS14135 (D3880_14140)	-	3102945..3104192 (-)	1248	WP_119894080.1	lipoprotein-releasing ABC transporter permease subunit	-
D3880_RS14140 (D3880_14145)	-	3104291..3104863 (+)	573	WP_119894081.1	PilZ domain-containing protein	-
D3880_RS14145 (D3880_14150)	-	3104895..3105218 (+)	324	WP_119894082.1	phosphodiesterase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 80103.93 Da
• Isoelectric Point: 9.5910

>NTDB_id=315706 D3880_RS14115 WP_119894076.1 3098057..3100282(-) (comA) [Pseudomonas cavernae strain K2W31S-8]
MRTGMLALAVGLLALRFLPALPPVWLLLVLPLVGLMALPFRSYPLAFFLFGFSWACASAHWALSDRLVPELDGRTLILQG
LVTGLPEHDTGVVRFQLEQVVARRAKLPQRLRLAWYDGPPVQAGERWQLAVKLKRGHGLVNPQSFDYEAWLLAQRIGAVG
TVKRGERLSPAQGASAWRDELRQRLLAVDAFGRQGALAALVLGDGSGLSVADWRVLQDTGTVHLLVISGQHVALLAALVY
GLVAGLARLGLWPSRWPWLPWACALAFAAALGYGLLAGFEVPVRRACLMVAMVLLWRLRFRHLGVWLPWLLALNGVLLAE
PLASLQPGFWLSFAAVAVLALVFSGRLGAWSWWHSWGRVQWTMAIGLLPALLALGLPLSASGPLANLIAEPWVSLAVVPL
ALLGTVLLPLPGLGEAVLWLAGGLLELLFRVLGMIAAGAPAWQATALPFWAWLLSACGALLLLLPTGIPMRALGLAMLLP
CFFPPPNSPAPGRAEVWLLDVGQGLAVLLRTHEHALLYDAGPRYGDFDIGERVVLPSLRGLDVRRLDLLLLSHADSDHAG
GAPAVQRGLPIDQVLSGEAAALPPVLGAEPCVDGASWSWDGVRFTTWRSAVAQEGNPASCVLRVEANGEALLLTGDIDAR
VERALLDAGREVRADWLLAPHHGSRSSSTAAFIKAVQPRAVLFSRGAHNAFGHPHPQVVARYRALQVRAYDTVENGALRI
ELGAHRDAHGLREQGRFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=315706 D3880_RS14115 WP_119894076.1 3098057..3100282(-) (comA) [Pseudomonas cavernae strain K2W31S-8]
ATGCGCACAGGGATGCTGGCGCTCGCCGTGGGGCTATTGGCCCTGCGTTTTCTCCCGGCGTTGCCGCCGGTGTGGTTGCT
GCTGGTTCTGCCGCTGGTCGGCCTGATGGCGCTGCCGTTTCGCAGCTATCCGCTGGCGTTCTTTCTCTTCGGCTTCAGCT
GGGCCTGCGCTTCGGCGCACTGGGCGCTGAGCGATCGCCTGGTTCCCGAGTTGGATGGTCGCACCCTGATCTTGCAGGGT
CTGGTGACCGGGCTGCCGGAGCACGATACCGGGGTAGTGCGCTTTCAGCTCGAACAGGTCGTTGCGCGGCGCGCCAAGCT
GCCGCAGCGTCTACGCCTGGCCTGGTATGACGGCCCCCCAGTGCAGGCCGGCGAGCGCTGGCAACTGGCCGTCAAGCTCA
AGCGGGGCCATGGGCTGGTCAATCCGCAGTCGTTCGACTACGAGGCCTGGTTGCTGGCGCAGCGCATTGGCGCCGTTGGC
ACAGTCAAGCGCGGCGAGCGCCTGAGCCCGGCGCAGGGCGCGTCGGCCTGGCGCGATGAGTTGCGCCAGCGCCTGCTCGC
AGTCGATGCCTTCGGTCGCCAGGGCGCGCTGGCGGCCCTGGTACTGGGGGACGGCTCGGGACTTTCGGTCGCCGACTGGC
GCGTGCTGCAGGACACCGGCACCGTGCATTTACTGGTGATCTCCGGCCAGCATGTGGCGTTGCTGGCGGCGCTGGTTTAT
GGCCTGGTGGCCGGGCTGGCACGTTTGGGCCTGTGGCCAAGTCGCTGGCCCTGGCTGCCTTGGGCCTGTGCGCTGGCATT
CGCCGCGGCGCTCGGCTATGGCCTGCTCGCCGGCTTCGAGGTGCCGGTGCGGCGCGCTTGCCTGATGGTGGCGATGGTGT
TGCTCTGGCGCCTGCGTTTTCGCCATCTGGGGGTATGGCTGCCCTGGCTGTTGGCGCTCAATGGCGTACTGCTGGCGGAG
CCGCTGGCCAGCTTGCAGCCGGGTTTTTGGTTGTCGTTCGCCGCCGTGGCGGTGCTTGCCCTGGTGTTCAGCGGGCGTCT
GGGTGCCTGGTCCTGGTGGCACAGTTGGGGTCGGGTGCAGTGGACCATGGCCATCGGGTTATTGCCGGCGCTGCTAGCCC
TTGGGCTGCCGCTCAGCGCCAGCGGACCGCTGGCCAATCTGATCGCGGAGCCTTGGGTCAGTCTGGCCGTGGTGCCGCTG
GCCTTGCTCGGCACAGTGCTGCTGCCATTGCCCGGGCTGGGTGAGGCCGTGCTGTGGCTGGCGGGTGGATTGCTGGAGCT
GTTGTTCCGTGTACTCGGCATGATCGCCGCCGGGGCTCCGGCCTGGCAGGCCACGGCATTGCCATTTTGGGCTTGGCTGC
TGAGTGCCTGCGGGGCGTTGTTGCTGCTCCTGCCGACCGGTATCCCCATGCGTGCGTTGGGGCTGGCCATGCTGCTGCCG
TGCTTCTTTCCGCCACCGAACTCGCCGGCGCCGGGGCGTGCGGAGGTCTGGTTATTGGATGTCGGTCAGGGCCTGGCGGT
GCTGCTGCGCACCCATGAACATGCGCTGCTGTATGACGCCGGGCCGCGCTATGGCGACTTCGACATCGGCGAGCGGGTGG
TGTTGCCCTCGTTGCGCGGGCTGGATGTGCGGCGCTTGGATTTGCTGCTGCTCAGCCATGCCGATAGCGACCATGCCGGC
GGCGCCCCAGCCGTGCAGCGCGGACTACCAATAGACCAAGTGCTCAGCGGCGAGGCCGCGGCGTTGCCACCCGTGTTAGG
GGCCGAGCCATGTGTCGACGGTGCCAGTTGGAGCTGGGATGGGGTGCGATTCACCACCTGGCGCTCGGCCGTAGCGCAGG
AGGGCAATCCGGCCAGTTGCGTGTTGCGGGTCGAAGCCAATGGCGAAGCTCTGCTATTGACCGGCGATATCGATGCGCGC
GTCGAGCGGGCATTGCTCGATGCCGGTCGCGAGGTGCGGGCCGATTGGCTGCTGGCGCCACATCACGGCAGTCGCAGCTC
TTCGACGGCGGCCTTTATCAAGGCGGTGCAGCCGCGCGCGGTGCTGTTCTCCCGGGGTGCGCACAACGCTTTCGGTCATC
CGCATCCTCAGGTCGTGGCGCGCTATCGGGCGCTGCAGGTGCGGGCCTACGACACCGTGGAAAATGGCGCCCTGCGCATC
GAATTAGGCGCCCATCGCGACGCTCACGGTTTGCGCGAACAGGGCCGGTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (500-680)

• Domain of unknown function (DUF4131) (DUF4131) (22-167)

• Competence protein (Competence) (200-464)

3D structure

• AlphaFold DB: A0A385Z3Y8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	65.551	96.761	0.634
comA	Ralstonia pseudosolanacearum GMI1000	36.418	100	0.414