Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   D5R92_RS10060 Genome accession   NZ_CP032401
Coordinates   2073615..2074925 (+) Length   436 a.a.
NCBI ID   WP_003099509.1    Uniprot ID   A0A3L8GJR1
Organism   Streptococcus iniae strain GX005     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2068615..2079925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5R92_RS10040 (D5R92_10040) pstB 2068762..2069520 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  D5R92_RS10045 (D5R92_10045) phoU 2069575..2070228 (+) 654 WP_003099503.1 phosphate signaling complex protein PhoU -
  D5R92_RS10050 (D5R92_10050) - 2070290..2072827 (+) 2538 Protein_1906 M1 family metallopeptidase -
  D5R92_RS10055 (D5R92_10055) ciaR 2072948..2073622 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  D5R92_RS10060 (D5R92_10060) ciaH 2073615..2074925 (+) 1311 WP_003099509.1 cell wall metabolism sensor histidine kinase WalK Regulator
  D5R92_RS10065 (D5R92_10065) rpsT 2075097..2075339 (-) 243 WP_080613191.1 30S ribosomal protein S20 -
  D5R92_RS10070 (D5R92_10070) coaA 2075399..2076319 (-) 921 WP_003099512.1 type I pantothenate kinase -
  D5R92_RS10075 (D5R92_10075) - 2076580..2077179 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  D5R92_RS10080 (D5R92_10080) - 2077166..2078443 (+) 1278 WP_003099515.1 pyrimidine-nucleoside phosphorylase -
  D5R92_RS10085 (D5R92_10085) deoC 2078455..2079117 (+) 663 WP_003099517.1 deoxyribose-phosphate aldolase -
  D5R92_RS10090 (D5R92_10090) - 2079089..2079493 (+) 405 WP_230453495.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49969.52 Da        Isoelectric Point: 9.1099

>NTDB_id=315525 D5R92_RS10060 WP_003099509.1 2073615..2074925(+) (ciaH) [Streptococcus iniae strain GX005]
MANLKRIYQSDNFGHFFHFFAVFTGIFVVMTMIIIQIMQYGVYSSVDSSLLAVSKNSSVYANLTMERMTSFYFDNQEDAF
KNGTEVFKAALVEQPVANTDIILFSSNGTVLNSFDALSGFQNFTLKTNELNAIRTRKLMNFYGHEEKYHTLTVKIHSNRY
PAVAYLMAVVNVEQLDRANERYERIIVLVMITFWFISVLASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNETILENSEPIASSLEEVRNMKILTTNLLNLARRDDGINPELVDVDASFFDAMFENFNLVAEDYGKDFHFEN
QVKRTIKMDKSLLKQLITILFDNALKYTDSDGQISISVRTTDKNLMVRVLDDGPGIKDMDKKKVFDRFYRVDKARTRTKG
GFGLGLSLAKQIVASLNGTISVKDNKPKGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=315525 D5R92_RS10060 WP_003099509.1 2073615..2074925(+) (ciaH) [Streptococcus iniae strain GX005]
ATGGCTAATTTAAAACGTATTTACCAGTCAGATAATTTTGGGCATTTTTTCCATTTTTTTGCAGTCTTTACAGGAATATT
TGTTGTCATGACCATGATTATCATTCAAATCATGCAGTACGGTGTTTATTCTTCGGTAGATAGTAGTCTACTTGCTGTGT
CAAAAAATTCATCGGTTTATGCTAATTTAACCATGGAACGAATGACCTCATTTTACTTTGATAATCAAGAGGATGCTTTT
AAAAATGGAACTGAAGTCTTTAAAGCAGCCTTAGTTGAACAACCAGTTGCCAATACGGATATTATCCTCTTTAGTTCTAA
CGGAACGGTTTTAAATAGCTTTGATGCGCTATCGGGTTTTCAAAATTTTACCTTAAAAACAAATGAATTAAATGCCATTC
GAACACGGAAATTGATGAATTTTTACGGGCATGAAGAAAAATACCATACGCTGACAGTTAAGATTCATTCCAATAGGTAC
CCAGCGGTGGCTTACCTAATGGCAGTTGTCAATGTGGAACAATTGGACCGTGCCAATGAGCGCTATGAACGAATCATTGT
TCTTGTTATGATAACTTTCTGGTTTATTTCTGTTTTGGCCAGTATATACCTTGCAAAATGGAGTCGTAAACCAATTCTTG
AAAGTTATGAGAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGAACTCCCTTAGCAGTATTACAAAATCGC
TTAGAGACCCTGTTTAGAAAACCTAATGAAACAATTCTGGAAAACAGTGAACCAATTGCTTCGAGTTTAGAAGAAGTGCG
CAATATGAAGATCTTAACCACAAATTTATTGAATCTTGCCAGACGCGATGATGGGATTAATCCAGAACTCGTTGATGTGG
ATGCAAGCTTTTTTGACGCTATGTTTGAAAACTTCAACTTAGTAGCTGAAGATTATGGTAAAGACTTCCATTTTGAAAAT
CAGGTTAAGCGGACAATAAAAATGGATAAATCTTTATTAAAACAATTGATTACCATTTTATTTGATAATGCTTTGAAATA
CACGGACTCTGATGGGCAAATTTCAATTAGTGTTCGAACAACAGATAAAAATTTAATGGTCAGAGTGCTAGATGATGGTC
CTGGAATAAAAGACATGGATAAAAAGAAAGTTTTTGACCGCTTCTATCGTGTTGATAAGGCTAGAACACGTACTAAAGGT
GGATTTGGTTTGGGACTTTCTTTAGCAAAACAGATTGTTGCTTCCTTAAATGGAACAATATCAGTTAAAGACAATAAACC
AAAAGGGACAATATTTGAAGTTAAACTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GJR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.275

99.312

0.569
  ciaH Streptococcus pneumoniae Rx1

51.835

100

0.518
  ciaH Streptococcus pneumoniae D39

51.835

100

0.518
  ciaH Streptococcus pneumoniae R6

51.835

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.835

100

0.518

Multiple sequence alignment