Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SEZ_RS08110 Genome accession   NC_011134
Coordinates   1710413..1711099 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705413..1716099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS08090 (Sez_1662) dnaI 1706178..1707086 (-) 909 WP_012516249.1 primosomal protein DnaI -
  SEZ_RS08095 (Sez_1663) - 1707087..1708250 (-) 1164 WP_172453605.1 helicase loader -
  SEZ_RS08100 (Sez_1664) nrdR 1708234..1708728 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  SEZ_RS08105 (Sez_1665) - 1708919..1710409 (-) 1491 WP_012516252.1 HAMP domain-containing histidine kinase -
  SEZ_RS08110 (Sez_1666) covR 1710413..1711099 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  SEZ_RS08115 (Sez_1667) - 1711285..1711818 (-) 534 WP_012516254.1 DUF177 domain-containing protein -
  SEZ_RS08120 (Sez_1668) htpX 1712106..1712999 (-) 894 WP_012516255.1 zinc metalloprotease HtpX -
  SEZ_RS08125 (Sez_1669) - 1713031..1713588 (-) 558 WP_012677410.1 LemA family protein -
  SEZ_RS08130 (Sez_1670) rsmG 1713724..1714437 (+) 714 WP_012516257.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=31391 SEZ_RS08110 WP_012516253.1 1710413..1711099(-) (covR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=31391 SEZ_RS08110 WP_012516253.1 1710413..1711099(-) (covR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGATTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCTGGCTTGGATCGTGGTGCTGACGATTACATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment