Detailed information NTG0313797

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: D3C65_RS24730
• Genome accession: NZ_CP032126
• Coordinates: 5202332..5203669 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PAO1161
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5197332..5208669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D3C65_RS24705 (D3C65_24680)	pgeF	5197475..5198203 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
D3C65_RS24710 (D3C65_24685)	rluD	5198200..5199162 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
D3C65_RS24715 (D3C65_24690)	-	5199308..5200333 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
D3C65_RS24720 (D3C65_24695)	-	5200490..5200735 (+)	246	WP_003102591.1	PP0621 family protein	-
D3C65_RS24725 (D3C65_24700)	pilS	5200725..5202317 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
D3C65_RS24730 (D3C65_24705)	pilR	5202332..5203669 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
D3C65_RS24735 (D3C65_24710)	thiO	5203715..5204809 (-)	1095	WP_010895678.1	glycine oxidase ThiO	-
D3C65_RS24740 (D3C65_24715)	-	5204944..5205453 (+)	510	WP_003112829.1	Tfp pilus assembly protein FimT/FimU	-
D3C65_RS24745 (D3C65_24720)	-	5205559..5206065 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
D3C65_RS24750 (D3C65_24725)	pilV	5206056..5206613 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
D3C65_RS24755 (D3C65_24730)	pilW	5206610..5207434 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
D3C65_RS24760 (D3C65_24735)	pilX	5207431..5208018 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=313797 D3C65_RS24730 WP_003094694.1 5202332..5203669(+) (pilR) [Pseudomonas aeruginosa strain PAO1161]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=313797 D3C65_RS24730 WP_003094694.1 5202332..5203669(+) (pilR) [Pseudomonas aeruginosa strain PAO1161]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384