Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   E4U67_RS25655 Genome accession   NZ_CP038360
Coordinates   5196578..5197603 (+) Length   341 a.a.
NCBI ID   WP_000644904.1    Uniprot ID   P0ACN8
Organism   Escherichia coli O157:H7 strain F7386     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5191578..5202603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4U67_RS25645 (E4U67_26355) rpmE 5193809..5194021 (-) 213 WP_000710769.1 50S ribosomal protein L31 -
  E4U67_RS25650 (E4U67_26360) priA 5194224..5196422 (+) 2199 WP_001301674.1 primosomal protein N' Machinery gene
  E4U67_RS25655 (E4U67_26365) cytR 5196578..5197603 (+) 1026 WP_000644904.1 DNA-binding transcriptional regulator CytR Regulator
  E4U67_RS25660 (E4U67_26370) ftsN 5197695..5198654 (+) 960 WP_000068837.1 cell division protein FtsN -
  E4U67_RS25665 (E4U67_26375) hslV 5198747..5199277 (+) 531 WP_000208242.1 ATP-dependent protease subunit HslV -
  E4U67_RS25670 (E4U67_26380) hslU 5199287..5200618 (+) 1332 WP_001293341.1 HslU--HslV peptidase ATPase subunit -
  E4U67_RS25675 (E4U67_26385) menA 5200685..5201611 (+) 927 WP_001308187.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase -
  E4U67_RS25680 (E4U67_26390) rraA 5201704..5202189 (+) 486 WP_000872908.1 ribonuclease E activity regulator RraA -

Sequence

Protein


Download         Length: 341 a.a.        Molecular weight: 37819.78 Da        Isoelectric Point: 6.3842

>NTDB_id=313028 E4U67_RS25655 WP_000644904.1 5196578..5197603(+) (cytR) [Escherichia coli O157:H7 strain F7386]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide


Download         Length: 1026 bp        

>NTDB_id=313028 E4U67_RS25655 WP_000644904.1 5196578..5197603(+) (cytR) [Escherichia coli O157:H7 strain F7386]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAAGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGTGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(11-56)

Periplasmic binding protein-like domain (Peripla_BP_3)

(176-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

64.179

98.24

0.63
  cytR Vibrio cholerae C6706

65.443

95.894

0.628

Multiple sequence alignment