Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | NGK_RS08820 | Genome accession | NC_011035 |
| Coordinates | 1619499..1619948 (-) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae NCCP11945 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1587598..1619250 | 1619499..1619948 | flank | 249 |
Gene organization within MGE regions
Location: 1587598..1619948
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NGK_RS08565 (NGK_1912) | - | 1587626..1588600 (-) | 975 | WP_003689550.1 | SIS domain-containing protein | - |
| NGK_RS08570 (NGK_1913) | tal | 1588697..1589752 (+) | 1056 | WP_003695503.1 | transaldolase | - |
| NGK_RS16300 (NGK_1914) | - | 1589764..1589898 (+) | 135 | WP_012503902.1 | hypothetical protein | - |
| NGK_RS08575 | - | 1589903..1590193 (+) | 291 | WP_003689553.1 | hypothetical protein | - |
| NGK_RS08580 (NGK_1916) | gluQRS | 1590210..1591097 (+) | 888 | WP_003689554.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| NGK_RS08585 (NGK_1917) | dusA | 1591167..1592183 (-) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| NGK_RS08590 (NGK_1918) | - | 1592303..1593457 (+) | 1155 | WP_003697468.1 | tyrosine-type recombinase/integrase | - |
| NGK_RS08595 (NGK_1919) | - | 1593507..1593773 (-) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| NGK_RS08600 (NGK_1920) | - | 1593881..1594828 (-) | 948 | WP_012503904.1 | hypothetical protein | - |
| NGK_RS15505 (NGK_1921) | - | 1594800..1595030 (-) | 231 | WP_003689156.1 | hypothetical protein | - |
| NGK_RS08610 (NGK_1922) | - | 1595027..1596010 (-) | 984 | WP_041421310.1 | phage associated protein | - |
| NGK_RS08615 (NGK_1923) | - | 1596121..1596336 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NGK_RS08620 (NGK_1924) | - | 1596388..1596879 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| NGK_RS08625 (NGK_1925) | - | 1596876..1597058 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NGK_RS08630 (NGK_1926) | - | 1597198..1597884 (-) | 687 | WP_012503754.1 | phage replication initiation protein, NGO0469 family | - |
| NGK_RS08635 (NGK_1927) | - | 1597953..1598114 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| NGK_RS08640 | - | 1598111..1598389 (-) | 279 | WP_041421244.1 | NGO1622 family putative holin | - |
| NGK_RS08645 | - | 1598542..1598874 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| NGK_RS08650 | - | 1599015..1599302 (-) | 288 | WP_041421246.1 | hypothetical protein | - |
| NGK_RS08655 (NGK_1929) | - | 1599299..1599775 (-) | 477 | WP_012504141.1 | DUF6948 domain-containing protein | - |
| NGK_RS08660 (NGK_1930) | - | 1599808..1600008 (-) | 201 | WP_003704298.1 | hypothetical protein | - |
| NGK_RS08665 (NGK_1931) | - | 1600492..1600710 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| NGK_RS08670 (NGK_1932) | - | 1600727..1601086 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| NGK_RS08675 (NGK_1933) | - | 1601087..1601626 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| NGK_RS08680 (NGK_1934) | - | 1601786..1602490 (-) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| NGK_RS13520 | - | 1602618..1602833 (+) | 216 | WP_223169978.1 | helix-turn-helix domain-containing protein | - |
| NGK_RS08685 (NGK_1935) | - | 1602913..1603068 (+) | 156 | WP_003691446.1 | hypothetical protein | - |
| NGK_RS08690 (NGK_1936) | - | 1603045..1603233 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| NGK_RS08695 (NGK_1937) | - | 1603406..1603633 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| NGK_RS16450 | - | 1603630..1604716 (+) | 1087 | Protein_1632 | helix-turn-helix domain-containing protein | - |
| NGK_RS08710 (NGK_1940) | - | 1604728..1605507 (+) | 780 | WP_041421353.1 | ATP-binding protein | - |
| NGK_RS08715 (NGK_1941) | - | 1605577..1605807 (+) | 231 | WP_041421301.1 | hypothetical protein | - |
| NGK_RS08720 (NGK_1942) | - | 1605821..1606315 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NGK_RS08725 | - | 1606490..1606639 (+) | 150 | WP_041421445.1 | hypothetical protein | - |
| NGK_RS16045 (NGK_1944) | - | 1606668..1606949 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NGK_RS08735 (NGK_1945) | - | 1606940..1607320 (+) | 381 | WP_041421299.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NGK_RS08740 (NGK_1947) | - | 1607649..1608611 (-) | 963 | WP_012503930.1 | IS110 family transposase | - |
| NGK_RS08745 (NGK_1949) | - | 1609137..1609496 (-) | 360 | WP_003689732.1 | hypothetical protein | - |
| NGK_RS08750 (NGK_1950) | - | 1609617..1610689 (-) | 1073 | Protein_1641 | zonular occludens toxin domain-containing protein | - |
| NGK_RS08755 (NGK_1951) | - | 1610699..1610989 (-) | 291 | WP_012503936.1 | DUF2523 domain-containing protein | - |
| NGK_RS08760 (NGK_1952) | - | 1610968..1612557 (-) | 1590 | WP_012503913.1 | IgG-binding virulence factor TspB family protein | - |
| NGK_RS08765 | - | 1612499..1612816 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| NGK_RS08770 (NGK_1953) | - | 1612944..1613222 (-) | 279 | WP_003691583.1 | hypothetical protein | - |
| NGK_RS08775 (NGK_1954) | - | 1613229..1613447 (-) | 219 | WP_003691584.1 | major capsid protein | - |
| NGK_RS08780 (NGK_1955) | - | 1613521..1613718 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| NGK_RS08785 (NGK_1956) | - | 1613723..1614013 (-) | 291 | WP_012503914.1 | hypothetical protein | - |
| NGK_RS08790 (NGK_1957) | - | 1614058..1615407 (-) | 1350 | WP_025455830.1 | replication initiation factor domain-containing protein | - |
| NGK_RS08795 (NGK_1958) | - | 1615546..1615968 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| NGK_RS16050 (NGK_1959) | - | 1615974..1616570 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| NGK_RS16055 (NGK_1960) | - | 1616760..1617617 (-) | 858 | WP_012503917.1 | ATP-binding protein | - |
| NGK_RS08805 (NGK_1961) | - | 1617631..1617960 (-) | 330 | WP_002234365.1 | DNA cytosine methyltransferase | - |
| NGK_RS08810 (NGK_1962) | - | 1617999..1618607 (-) | 609 | WP_080229275.1 | DNA cytosine methyltransferase | - |
| NGK_RS08815 (NGK_1963) | - | 1618976..1619122 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| NGK_RS08820 | comP | 1619499..1619948 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=31238 NGK_RS08820 WP_002214937.1 1619499..1619948(-) (comP) [Neisseria gonorrhoeae NCCP11945]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=31238 NGK_RS08820 WP_002214937.1 1619499..1619948(-) (comP) [Neisseria gonorrhoeae NCCP11945]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |