Detailed information NTG0312275

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1096_RS08990
• Genome accession: NZ_CP031874
• Coordinates: 1950555..1951211 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain S1421
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1945555..1956211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1096_RS08970 (D1096_09040)	nanA	1945929..1946807 (+)	879	WP_012263384.1	N-acetylneuraminate lyase	-
D1096_RS08975 (D1096_09045)	nagB	1946857..1947660 (+)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
D1096_RS08980 (D1096_09050)	nagA	1947712..1948857 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1096_RS08985 (D1096_09055)	fumC	1949006..1950400 (-)	1395	WP_012263385.1	class II fumarate hydratase	-
D1096_RS08990 (D1096_09060)	sxy/tfoX	1950555..1951211 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1096_RS08995 (D1096_09065)	rpsJ	1951619..1951930 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1096_RS09000 (D1096_09070)	rplC	1951956..1952582 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1096_RS09005 (D1096_09075)	rplD	1952598..1953200 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1096_RS09010 (D1096_09080)	rplW	1953197..1953502 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1096_RS09015 (D1096_09085)	rplB	1953523..1954344 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1096_RS09020 (D1096_09090)	rpsS	1954372..1954647 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1096_RS09025 (D1096_09095)	rplV	1954658..1954990 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1096_RS09030 (D1096_09100)	rpsC	1955009..1955716 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1096_RS09035 (D1096_09105)	rplP	1955730..1956140 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312275 D1096_RS08990 WP_005609196.1 1950555..1951211(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain S1421]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312275 D1096_RS08990 WP_005609196.1 1950555..1951211(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain S1421]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376