Detailed information NTG0312248

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1097_RS09475
• Genome accession: NZ_CP031873
• Coordinates: 2011146..2011802 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 4 str. M62
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2006146..2016802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1097_RS09455 (D1097_09500)	nanA	2006519..2007397 (+)	879	WP_005605800.1	N-acetylneuraminate lyase	-
D1097_RS09460 (D1097_09505)	nagB	2007447..2008250 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1097_RS09465 (D1097_09510)	nagA	2008302..2009447 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1097_RS09470 (D1097_09515)	fumC	2009597..2010991 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1097_RS09475 (D1097_09520)	sxy/tfoX	2011146..2011802 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1097_RS09480 (D1097_09525)	rpsJ	2012210..2012521 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1097_RS09485 (D1097_09530)	rplC	2012547..2013173 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1097_RS09490 (D1097_09535)	rplD	2013189..2013791 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1097_RS09495 (D1097_09540)	rplW	2013788..2014093 (+)	306	WP_005605807.1	50S ribosomal protein L23	-
D1097_RS09500 (D1097_09545)	rplB	2014114..2014935 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1097_RS09505 (D1097_09550)	rpsS	2014963..2015238 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1097_RS09510 (D1097_09555)	rplV	2015249..2015581 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1097_RS09515 (D1097_09560)	rpsC	2015600..2016307 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1097_RS09520 (D1097_09565)	rplP	2016321..2016731 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312248 D1097_RS09475 WP_005609196.1 2011146..2011802(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 4 str. M62]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312248 D1097_RS09475 WP_005609196.1 2011146..2011802(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 4 str. M62]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376