Detailed information NTG0312217

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1100_RS07840
• Genome accession: NZ_CP031869
• Coordinates: 1661659..1662315 (+)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain WF83
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1656659..1667315

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1100_RS07795 (D1100_07845)	rplP	1656730..1657140 (-)	411	WP_005599294.1	50S ribosomal protein L16	-
D1100_RS07800 (D1100_07850)	rpsC	1657154..1657861 (-)	708	WP_005599293.1	30S ribosomal protein S3	-
D1100_RS07805 (D1100_07855)	rplV	1657880..1658212 (-)	333	WP_005599292.1	50S ribosomal protein L22	-
D1100_RS07810 (D1100_07860)	rpsS	1658223..1658498 (-)	276	WP_005539416.1	30S ribosomal protein S19	-
D1100_RS07815 (D1100_07865)	rplB	1658526..1659347 (-)	822	WP_005599291.1	50S ribosomal protein L2	-
D1100_RS07820 (D1100_07870)	rplW	1659368..1659673 (-)	306	WP_005599290.1	50S ribosomal protein L23	-
D1100_RS07825 (D1100_07875)	rplD	1659670..1660272 (-)	603	WP_005599282.1	50S ribosomal protein L4	-
D1100_RS07830 (D1100_07880)	rplC	1660288..1660914 (-)	627	WP_005599280.1	50S ribosomal protein L3	-
D1100_RS07835 (D1100_07885)	rpsJ	1660940..1661251 (-)	312	WP_001181005.1	30S ribosomal protein S10	-
D1100_RS07840 (D1100_07890)	sxy/tfoX	1661659..1662315 (+)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1100_RS07845 (D1100_07895)	fumC	1662470..1663864 (+)	1395	WP_005605803.1	class II fumarate hydratase	-
D1100_RS07850 (D1100_07900)	nagA	1664013..1665158 (-)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1100_RS07855 (D1100_07905)	nagB	1665210..1666013 (-)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1100_RS07860 (D1100_07910)	nanA	1666063..1666941 (-)	879	WP_005599265.1	N-acetylneuraminate lyase	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312217 D1100_RS07840 WP_005609196.1 1661659..1662315(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain WF83]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312217 D1100_RS07840 WP_005609196.1 1661659..1662315(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain WF83]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376