Detailed information NTG0312197

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1101_RS09600
• Genome accession: NZ_CP031866
• Coordinates: 2027325..2027981 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 8 str. 405
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2022325..2032981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1101_RS09580 (D1101_09640)	nanA	2022698..2023576 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1101_RS09585 (D1101_09645)	nagB	2023626..2024429 (+)	804	WP_218633941.1	glucosamine-6-phosphate deaminase	-
D1101_RS09590 (D1101_09650)	nagA	2024481..2025626 (+)	1146	WP_218633942.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1101_RS09595 (D1101_09655)	fumC	2025776..2027170 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1101_RS09600 (D1101_09660)	sxy/tfoX	2027325..2027981 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1101_RS09605 (D1101_09665)	rpsJ	2028389..2028700 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1101_RS09610 (D1101_09670)	rplC	2028726..2029352 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1101_RS09615 (D1101_09675)	rplD	2029368..2029970 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1101_RS09620 (D1101_09680)	rplW	2029967..2030272 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1101_RS09625 (D1101_09685)	rplB	2030293..2031114 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1101_RS09630 (D1101_09690)	rpsS	2031142..2031417 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1101_RS09635 (D1101_09695)	rplV	2031428..2031760 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1101_RS09640 (D1101_09700)	rpsC	2031779..2032486 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1101_RS09645 (D1101_09705)	rplP	2032500..2032910 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312197 D1101_RS09600 WP_005609196.1 2027325..2027981(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312197 D1101_RS09600 WP_005609196.1 2027325..2027981(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376