Detailed information NTG0312144

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1103_RS09455
• Genome accession: NZ_CP031864
• Coordinates: 2024823..2025479 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 10 str. D13039
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2019823..2030479

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1103_RS09435 (D1103_09510)	nanA	2020197..2021075 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1103_RS09440 (D1103_09515)	nagB	2021125..2021928 (+)	804	WP_005613319.1	glucosamine-6-phosphate deaminase	-
D1103_RS09445 (D1103_09520)	nagA	2021980..2023125 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1103_RS09450 (D1103_09525)	fumC	2023274..2024668 (-)	1395	WP_005613320.1	class II fumarate hydratase	-
D1103_RS09455 (D1103_09530)	sxy/tfoX	2024823..2025479 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1103_RS09460 (D1103_09535)	rpsJ	2025887..2026198 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1103_RS09465 (D1103_09540)	rplC	2026224..2026850 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1103_RS09470 (D1103_09545)	rplD	2026866..2027468 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1103_RS09475 (D1103_09550)	rplW	2027465..2027770 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1103_RS09480 (D1103_09555)	rplB	2027791..2028612 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1103_RS09485 (D1103_09560)	rpsS	2028640..2028915 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1103_RS09490 (D1103_09565)	rplV	2028926..2029258 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1103_RS09495 (D1103_09570)	rpsC	2029277..2029984 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1103_RS09500 (D1103_09575)	rplP	2029998..2030408 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312144 D1103_RS09455 WP_005609196.1 2024823..2025479(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312144 D1103_RS09455 WP_005609196.1 2024823..2025479(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376