Detailed information NTG0312117

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1104_RS09630
• Genome accession: NZ_CP031863
• Coordinates: 2044158..2044814 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 11 str. 56153
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2039158..2049814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1104_RS09610 (D1104_09670)	nanA	2039532..2040410 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1104_RS09615 (D1104_09675)	nagB	2040460..2041263 (+)	804	WP_005610807.1	glucosamine-6-phosphate deaminase	-
D1104_RS09620 (D1104_09680)	nagA	2041315..2042460 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1104_RS09625 (D1104_09685)	fumC	2042609..2044003 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
D1104_RS09630 (D1104_09690)	sxy/tfoX	2044158..2044814 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1104_RS09635 (D1104_09695)	rpsJ	2045222..2045533 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1104_RS09640 (D1104_09700)	rplC	2045559..2046185 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1104_RS09645 (D1104_09705)	rplD	2046201..2046803 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1104_RS09650 (D1104_09710)	rplW	2046800..2047105 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1104_RS09655 (D1104_09715)	rplB	2047126..2047947 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1104_RS09660 (D1104_09720)	rpsS	2047975..2048250 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1104_RS09665 (D1104_09725)	rplV	2048261..2048593 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1104_RS09670 (D1104_09730)	rpsC	2048612..2049319 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1104_RS09675 (D1104_09735)	rplP	2049333..2049743 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312117 D1104_RS09630 WP_005609196.1 2044158..2044814(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 11 str. 56153]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312117 D1104_RS09630 WP_005609196.1 2044158..2044814(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 11 str. 56153]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376