Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   D1105_RS09145 Genome accession   NZ_CP031862
Coordinates   1970494..1971150 (-) Length   218 a.a.
NCBI ID   WP_005609196.1    Uniprot ID   A3N356
Organism   Actinobacillus pleuropneumoniae strain 8329     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1971558..1983837 1970494..1971150 flank 408


Gene organization within MGE regions


Location: 1970494..1983837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1105_RS09145 (D1105_09230) sxy/tfoX 1970494..1971150 (-) 657 WP_005609196.1 TfoX/Sxy family DNA transformation protein Regulator
  D1105_RS09150 (D1105_09235) rpsJ 1971558..1971869 (+) 312 WP_001181005.1 30S ribosomal protein S10 -
  D1105_RS09155 (D1105_09240) rplC 1971895..1972521 (+) 627 WP_005599280.1 50S ribosomal protein L3 -
  D1105_RS09160 (D1105_09245) rplD 1972537..1973139 (+) 603 WP_005599282.1 50S ribosomal protein L4 -
  D1105_RS09165 (D1105_09250) rplW 1973136..1973441 (+) 306 WP_005599290.1 50S ribosomal protein L23 -
  D1105_RS09170 (D1105_09255) rplB 1973462..1974283 (+) 822 WP_005599291.1 50S ribosomal protein L2 -
  D1105_RS09175 (D1105_09260) rpsS 1974311..1974586 (+) 276 WP_005539416.1 30S ribosomal protein S19 -
  D1105_RS09180 (D1105_09265) rplV 1974597..1974929 (+) 333 WP_005599292.1 50S ribosomal protein L22 -
  D1105_RS09185 (D1105_09270) rpsC 1974948..1975655 (+) 708 WP_005599293.1 30S ribosomal protein S3 -
  D1105_RS09190 (D1105_09275) rplP 1975669..1976079 (+) 411 WP_005599294.1 50S ribosomal protein L16 -
  D1105_RS09195 (D1105_09280) rpmC 1976079..1976270 (+) 192 WP_005599295.1 50S ribosomal protein L29 -
  D1105_RS09200 (D1105_09285) rpsQ 1976270..1976524 (+) 255 WP_005599296.1 30S ribosomal protein S17 -
  D1105_RS09205 (D1105_09290) rplN 1976764..1977135 (+) 372 WP_005619403.1 50S ribosomal protein L14 -
  D1105_RS09210 (D1105_09295) rplX 1977146..1977457 (+) 312 WP_005599300.1 50S ribosomal protein L24 -
  D1105_RS09215 (D1105_09300) rplE 1977475..1978014 (+) 540 WP_005619405.1 50S ribosomal protein L5 -
  D1105_RS09220 (D1105_09305) rpsN 1978026..1978331 (+) 306 WP_005602614.1 30S ribosomal protein S14 -
  D1105_RS09225 (D1105_09310) rpsH 1978368..1978760 (+) 393 WP_005619408.1 30S ribosomal protein S8 -
  D1105_RS09230 (D1105_09315) rplF 1978777..1979310 (+) 534 WP_005599308.1 50S ribosomal protein L6 -
  D1105_RS09235 (D1105_09320) rplR 1979325..1979678 (+) 354 WP_005599310.1 50S ribosomal protein L18 -
  D1105_RS09240 (D1105_09325) rpsE 1979693..1980193 (+) 501 WP_005599314.1 30S ribosomal protein S5 -
  D1105_RS09245 (D1105_09330) rpmD 1980200..1980379 (+) 180 WP_005599315.1 50S ribosomal protein L30 -
  D1105_RS09250 (D1105_09335) rplO 1980384..1980818 (+) 435 WP_005602615.1 50S ribosomal protein L15 -
  D1105_RS09255 (D1105_09340) secY 1980822..1982144 (+) 1323 WP_005602618.1 preprotein translocase subunit SecY -
  D1105_RS09260 (D1105_09345) rpmJ 1982170..1982283 (+) 114 WP_005599318.1 50S ribosomal protein L36 -
  D1105_RS09265 (D1105_09350) rpsM 1982420..1982776 (+) 357 WP_005599322.1 30S ribosomal protein S13 -
  D1105_RS09270 (D1105_09355) rpsK 1982793..1983182 (+) 390 WP_005599323.1 30S ribosomal protein S11 -
  D1105_RS09275 (D1105_09360) rpsD 1983211..1983837 (+) 627 WP_005599325.1 30S ribosomal protein S4 -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25633.15 Da        Isoelectric Point: 9.9359

>NTDB_id=312092 D1105_RS09145 WP_005609196.1 1970494..1971150(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 8329]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide


Download         Length: 657 bp        

>NTDB_id=312092 D1105_RS09145 WP_005609196.1 1970494..1971150(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 8329]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(120-196)

TfoX N-terminal domain (TfoX_N)

(13-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N356

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Actinobacillus pleuropneumoniae strain HS143

100

100

1
  sxy/tfoX Actinobacillus suis H91-0380

63.721

98.624

0.628
  sxy/tfoX Glaesserella parasuis strain SC1401

39.234

95.872

0.376

Multiple sequence alignment