Detailed information NTG0312065

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1106_RS09540
• Genome accession: NZ_CP031861
• Coordinates: 2026643..2027299 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain N 273
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2021643..2032299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1106_RS09520 (D1106_09560)	nanA	2022016..2022894 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1106_RS09525 (D1106_09565)	nagB	2022944..2023747 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1106_RS09530 (D1106_09570)	nagA	2023799..2024944 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1106_RS09535 (D1106_09575)	fumC	2025094..2026488 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1106_RS09540 (D1106_09580)	sxy/tfoX	2026643..2027299 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1106_RS09545 (D1106_09585)	rpsJ	2027707..2028018 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1106_RS09550 (D1106_09590)	rplC	2028044..2028670 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1106_RS09555 (D1106_09595)	rplD	2028686..2029288 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1106_RS09560 (D1106_09600)	rplW	2029285..2029590 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1106_RS09565 (D1106_09605)	rplB	2029611..2030432 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1106_RS09570 (D1106_09610)	rpsS	2030460..2030735 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1106_RS09575 (D1106_09615)	rplV	2030746..2031078 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1106_RS09580 (D1106_09620)	rpsC	2031097..2031804 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1106_RS09585 (D1106_09625)	rplP	2031818..2032228 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312065 D1106_RS09540 WP_005609196.1 2026643..2027299(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain N 273]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312065 D1106_RS09540 WP_005609196.1 2026643..2027299(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain N 273]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376