Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1106_RS04670 Genome accession   NZ_CP031861
Coordinates   1023166..1024368 (-) Length   400 a.a.
NCBI ID   WP_237594279.1    Uniprot ID   A0A9Q4H5M4
Organism   Actinobacillus pleuropneumoniae strain N 273     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1018166..1029368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1106_RS04645 (D1106_04665) lptE 1019966..1020460 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1106_RS04650 (D1106_04670) holA 1020569..1021594 (+) 1026 WP_005612206.1 DNA polymerase III subunit delta -
  D1106_RS04655 (D1106_04675) yacG 1021671..1021859 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1106_RS04660 (D1106_04680) coaE 1021841..1022479 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1106_RS04665 (D1106_04685) - 1022501..1023139 (-) 639 WP_005604550.1 prepilin peptidase -
  D1106_RS04670 (D1106_04690) pilC 1023166..1024368 (-) 1203 WP_237594279.1 type II secretion system F family protein Machinery gene
  D1106_RS04675 (D1106_04695) pilB 1024352..1025746 (-) 1395 WP_005601209.1 GspE/PulE family protein Machinery gene
  D1106_RS04680 (D1106_04700) pilA 1025764..1026210 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1106_RS04685 (D1106_04705) radA 1026392..1027771 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1106_RS04690 (D1106_04710) - 1027815..1028048 (-) 234 WP_005597399.1 YgjV family protein -
  D1106_RS04695 (D1106_04715) folA 1028175..1028663 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45590.06 Da        Isoelectric Point: 10.2657

>NTDB_id=312048 D1106_RS04670 WP_237594279.1 1023166..1024368(-) (pilC) [Actinobacillus pleuropneumoniae strain N 273]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVQIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=312048 D1106_RS04670 WP_237594279.1 1023166..1024368(-) (pilC) [Actinobacillus pleuropneumoniae strain N 273]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACAGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

50.126

99.25

0.498
  pilC Haemophilus influenzae Rd KW20

40.25

100

0.403
  pilC Haemophilus influenzae 86-028NP

39.25

100

0.393

Multiple sequence alignment