Detailed information NTG0312039

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1107_RS09010
• Genome accession: NZ_CP031860
• Coordinates: 1944663..1945319 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain 3906
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1939663..1950319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1107_RS08990 (D1107_09090)	nanA	1940037..1940915 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1107_RS08995 (D1107_09095)	nagB	1940965..1941768 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1107_RS09000 (D1107_09100)	nagA	1941820..1942965 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1107_RS09005 (D1107_09105)	fumC	1943114..1944508 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1107_RS09010 (D1107_09110)	sxy/tfoX	1944663..1945319 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1107_RS09015 (D1107_09115)	rpsJ	1945729..1946040 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1107_RS09020 (D1107_09120)	rplC	1946066..1946692 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1107_RS09025 (D1107_09125)	rplD	1946708..1947310 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1107_RS09030 (D1107_09130)	rplW	1947307..1947612 (+)	306	WP_237592754.1	50S ribosomal protein L23	-
D1107_RS09035 (D1107_09135)	rplB	1947633..1948454 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1107_RS09040 (D1107_09140)	rpsS	1948482..1948757 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1107_RS09045 (D1107_09145)	rplV	1948768..1949100 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1107_RS09050 (D1107_09150)	rpsC	1949119..1949826 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1107_RS09055 (D1107_09155)	rplP	1949840..1950250 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312039 D1107_RS09010 WP_005609196.1 1944663..1945319(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 3906]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312039 D1107_RS09010 WP_005609196.1 1944663..1945319(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 3906]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376