Detailed information NTG0311979

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1109_RS06925
• Genome accession: NZ_CP031858
• Coordinates: 1442372..1443028 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain A-85/14
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1437372..1448028

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1109_RS06905 (D1109_06920)	nanA	1437746..1438624 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1109_RS06910 (D1109_06925)	nagB	1438674..1439477 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1109_RS06915 (D1109_06930)	nagA	1439529..1440674 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1109_RS06920 (D1109_06935)	fumC	1440823..1442217 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1109_RS06925 (D1109_06940)	sxy/tfoX	1442372..1443028 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1109_RS06930 (D1109_06945)	rpsJ	1443436..1443747 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1109_RS06935 (D1109_06950)	rplC	1443773..1444399 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1109_RS06940 (D1109_06955)	rplD	1444415..1445017 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1109_RS06945 (D1109_06960)	rplW	1445014..1445319 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1109_RS06950 (D1109_06965)	rplB	1445340..1446161 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1109_RS06955 (D1109_06970)	rpsS	1446189..1446464 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1109_RS06960 (D1109_06975)	rplV	1446475..1446807 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1109_RS06965 (D1109_06980)	rpsC	1446826..1447533 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1109_RS06970 (D1109_06985)	rplP	1447547..1447957 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=311979 D1109_RS06925 WP_005609196.1 1442372..1443028(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain A-85/14]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=311979 D1109_RS06925 WP_005609196.1 1442372..1443028(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain A-85/14]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376