Detailed information NTG0311960

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1110_RS09440
• Genome accession: NZ_CP031856
• Coordinates: 2011080..2011736 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain 16287-1
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2006080..2016736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1110_RS09420 (D1110_09505)	nanA	2006453..2007331 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1110_RS09425 (D1110_09510)	nagB	2007381..2008184 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1110_RS09430 (D1110_09515)	nagA	2008236..2009381 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1110_RS09435 (D1110_09520)	fumC	2009531..2010925 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1110_RS09440 (D1110_09525)	sxy/tfoX	2011080..2011736 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1110_RS09445 (D1110_09530)	rpsJ	2012144..2012455 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1110_RS09450 (D1110_09535)	rplC	2012481..2013107 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1110_RS09455 (D1110_09540)	rplD	2013123..2013725 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1110_RS09460 (D1110_09545)	rplW	2013722..2014027 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1110_RS09465 (D1110_09550)	rplB	2014048..2014869 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1110_RS09470 (D1110_09555)	rpsS	2014897..2015172 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1110_RS09475 (D1110_09560)	rplV	2015183..2015515 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1110_RS09480 (D1110_09565)	rpsC	2015534..2016241 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1110_RS09485 (D1110_09570)	rplP	2016255..2016665 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=311960 D1110_RS09440 WP_005609196.1 2011080..2011736(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 16287-1]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=311960 D1110_RS09440 WP_005609196.1 2011080..2011736(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 16287-1]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376