Detailed information NTG0311934

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1111_RS08975
• Genome accession: NZ_CP031855
• Coordinates: 1934333..1934989 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain 7311555
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1929333..1939989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1111_RS08955 (D1111_09020)	nanA	1929706..1930584 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
D1111_RS08960 (D1111_09025)	nagB	1930634..1931437 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1111_RS08965 (D1111_09030)	nagA	1931489..1932634 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1111_RS08970 (D1111_09035)	fumC	1932784..1934178 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
D1111_RS08975 (D1111_09040)	sxy/tfoX	1934333..1934989 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1111_RS08980 (D1111_09045)	rpsJ	1935397..1935708 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1111_RS08985 (D1111_09050)	rplC	1935734..1936360 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1111_RS08990 (D1111_09055)	rplD	1936376..1936978 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1111_RS08995 (D1111_09060)	rplW	1936975..1937280 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1111_RS09000 (D1111_09065)	rplB	1937301..1938122 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1111_RS09005 (D1111_09070)	rpsS	1938150..1938425 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1111_RS09010 (D1111_09075)	rplV	1938436..1938768 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1111_RS09015 (D1111_09080)	rpsC	1938787..1939494 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1111_RS09020 (D1111_09085)	rplP	1939508..1939918 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=311934 D1111_RS08975 WP_005609196.1 1934333..1934989(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 7311555]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=311934 D1111_RS08975 WP_005609196.1 1934333..1934989(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain 7311555]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376