Detailed information NTG0311908

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1112_RS09070
• Genome accession: NZ_CP031854
• Coordinates: 1960748..1961404 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain ORG1224
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1955748..1966404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1112_RS09050 (D1112_09120)	nanA	1956122..1957000 (+)	879	WP_012263384.1	N-acetylneuraminate lyase	-
D1112_RS09055 (D1112_09125)	nagB	1957050..1957853 (+)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
D1112_RS09060 (D1112_09130)	nagA	1957905..1959050 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1112_RS09065 (D1112_09135)	fumC	1959199..1960593 (-)	1395	WP_012263385.1	class II fumarate hydratase	-
D1112_RS09070 (D1112_09140)	sxy/tfoX	1960748..1961404 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1112_RS09075 (D1112_09145)	rpsJ	1961812..1962123 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
D1112_RS09080 (D1112_09150)	rplC	1962149..1962775 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
D1112_RS09085 (D1112_09155)	rplD	1962791..1963393 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
D1112_RS09090 (D1112_09160)	rplW	1963390..1963695 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
D1112_RS09095 (D1112_09165)	rplB	1963716..1964537 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
D1112_RS09100 (D1112_09170)	rpsS	1964565..1964840 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
D1112_RS09105 (D1112_09175)	rplV	1964851..1965183 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
D1112_RS09110 (D1112_09180)	rpsC	1965202..1965909 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
D1112_RS09115 (D1112_09185)	rplP	1965923..1966333 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=311908 D1112_RS09070 WP_005609196.1 1960748..1961404(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain ORG1224]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=311908 D1112_RS09070 WP_005609196.1 1960748..1961404(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain ORG1224]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376