Detailed information NTG0310205

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: CH578_RS03940
• Genome accession: NZ_CP031690
• Coordinates: 758236..758928 (+)
• Length: 230 a.a.
• NCBI ID: WP_038440789.1
• Uniprot ID: A0AAJ8WR53
• Organism: Haemophilus influenzae strain P617-9224
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 753236..763928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CH578_RS03920 (CH578_03920)	ampD	754507..755067 (-)	561	WP_070828280.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
CH578_RS03925 (CH578_03925)	pilA	755182..755631 (+)	450	WP_011271973.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
CH578_RS03930 (CH578_03930)	pilB	755628..757022 (+)	1395	WP_011271972.1	GspE/PulE family protein	Machinery gene
CH578_RS03935 (CH578_03935)	pilC	757019..758239 (+)	1221	WP_011271971.1	type II secretion system F family protein	Machinery gene
CH578_RS03940 (CH578_03940)	pilD	758236..758928 (+)	693	WP_038440789.1	prepilin peptidase	Machinery gene
CH578_RS03945 (CH578_03945)	rho	758982..760244 (-)	1263	WP_005629550.1	transcription termination factor Rho	-
CH578_RS03950 (CH578_03950)	metJ	760492..760809 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
CH578_RS03955 (CH578_03955)	cueR	760823..761209 (-)	387	WP_005663006.1	Cu(I)-responsive transcriptional regulator	-
CH578_RS03960 (CH578_03960)	-	761286..761492 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
CH578_RS03965 (CH578_03965)	-	761567..761773 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-
CH578_RS03970 (CH578_03970)	-	761847..762053 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-
CH578_RS03975 (CH578_03975)	-	762127..762333 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
CH578_RS03980 (CH578_03980)	-	762407..762613 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26786.77 Da
• Isoelectric Point: 8.6895

>NTDB_id=310205 CH578_RS03940 WP_038440789.1 758236..758928(+) (pilD) [Haemophilus influenzae strain P617-9224]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide

• Length: 693 bp

>NTDB_id=310205 CH578_RS03940 WP_038440789.1 758236..758928(+) (pilD) [Haemophilus influenzae strain P617-9224]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (92-199)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Haemophilus influenzae 86-028NP	97.391	100	0.974
pilD	Haemophilus influenzae Rd KW20	95.652	100	0.957