Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ES300_RS09850 Genome accession   NZ_CP038251
Coordinates   1916572..1917066 (-) Length   164 a.a.
NCBI ID   WP_223842291.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1911572..1922066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS09820 (ES300_10330) - 1911882..1912757 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  ES300_RS09825 (ES300_10335) pstC 1912875..1913738 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  ES300_RS09830 (ES300_10340) pstA 1913731..1914546 (+) 816 WP_000049764.1 phosphate ABC transporter permease PstA -
  ES300_RS09835 (ES300_10345) pstB 1914548..1915300 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  ES300_RS09840 (ES300_10350) phoU 1915315..1915965 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  ES300_RS09845 (ES300_10355) - 1916006..1916449 (+) 444 Protein_1929 transposase -
  ES300_RS09850 (ES300_10360) comR 1916572..1917066 (-) 495 WP_223842291.1 helix-turn-helix transcriptional regulator Regulator
  ES300_RS09855 (ES300_10365) - 1917224..1918240 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ES300_RS09860 (ES300_10370) galU 1918262..1919161 (+) 900 WP_000202229.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  ES300_RS09865 (ES300_10375) - 1919228..1919905 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  ES300_RS09870 (ES300_10380) - 1919889..1920428 (-) 540 WP_000834308.1 5-formyltetrahydrofolate cyclo-ligase -
  ES300_RS09875 (ES300_10385) - 1920440..1921570 (-) 1131 WP_000885102.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19738.77 Da        Isoelectric Point: 4.8839

>NTDB_id=310159 ES300_RS09850 WP_223842291.1 1916572..1917066(-) (comR) [Streptococcus pneumoniae strain TVO_1901944]
MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLEVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=310159 ES300_RS09850 WP_223842291.1 1916572..1917066(-) (comR) [Streptococcus pneumoniae strain TVO_1901944]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)

Helix-turn-helix (HTH_3)

(26-77)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

53.333

73.171

0.39

Multiple sequence alignment