Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CH628_RS00185 Genome accession   NZ_CP031681
Coordinates   39739..40413 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain P669-6977     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34739..45413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH628_RS00165 (CH628_00165) hinT 36447..36797 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  CH628_RS00170 (CH628_00170) - 36797..37147 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  CH628_RS00175 (CH628_00175) nagZ 37151..38206 (+) 1056 WP_105892660.1 beta-N-acetylhexosaminidase -
  CH628_RS00180 (CH628_00180) rlmC 38199..39374 (+) 1176 WP_021034785.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  CH628_RS00185 (CH628_00185) crp 39739..40413 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  CH628_RS00190 (CH628_00190) - 40398..40649 (-) 252 WP_005647999.1 YheU family protein -
  CH628_RS00195 (CH628_00195) slmA 40671..41327 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  CH628_RS00200 (CH628_00200) dut 41331..41786 (-) 456 WP_005631431.1 dUTP diphosphatase -
  CH628_RS00205 (CH628_00205) coaBC 41834..43036 (-) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  CH628_RS00210 (CH628_00210) radC 43199..43868 (+) 670 Protein_38 DNA repair protein RadC -
  CH628_RS00215 (CH628_00215) rpmB 44082..44318 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  CH628_RS00220 (CH628_00220) rpmG 44330..44500 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=309865 CH628_RS00185 WP_005647998.1 39739..40413(-) (crp) [Haemophilus influenzae strain P669-6977]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=309865 CH628_RS00185 WP_005647998.1 39739..40413(-) (crp) [Haemophilus influenzae strain P669-6977]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment