Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   E4F32_RS01820 Genome accession   NZ_CP038180
Coordinates   393499..394131 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 388499..399131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4F32_RS01795 (E4F32_01795) yhfG 388631..388798 (+) 168 WP_000736860.1 YhfG family protein -
  E4F32_RS01800 (E4F32_01800) fic 388788..389390 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  E4F32_RS01805 (E4F32_01805) pabA 389422..389985 (+) 564 WP_134778495.1 aminodeoxychorismate synthase component 2 -
  E4F32_RS01810 (E4F32_01810) argD 390071..391291 (+) 1221 WP_024249933.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  E4F32_RS01815 (E4F32_01815) yhfK 391358..393448 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  E4F32_RS01820 (E4F32_01820) crp 393499..394131 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  E4F32_RS01825 (E4F32_01825) yhfA 394433..394837 (+) 405 WP_001148910.1 OsmC family protein -
  E4F32_RS01830 (E4F32_01830) prkB 394892..395761 (-) 870 WP_001274680.1 phosphoribulokinase -
  E4F32_RS01835 (E4F32_01835) yheU 395815..396033 (-) 219 WP_000907085.1 YheU family protein -
  E4F32_RS01840 (E4F32_01840) yheT 396027..397049 (-) 1023 WP_134778496.1 hydrolase -
  E4F32_RS01845 (E4F32_01845) yheS 397049..398962 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=309674 E4F32_RS01820 WP_000242755.1 393499..394131(-) (crp) [Escherichia coli strain]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=309674 E4F32_RS01820 WP_000242755.1 393499..394131(-) (crp) [Escherichia coli strain]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467