Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E4F32_RS00155 Genome accession   NZ_CP038180
Coordinates   27992..28582 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 22992..33582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4F32_RS00125 (E4F32_00125) yidF 23108..23605 (+) 498 WP_000148063.1 radical SAM protein -
  E4F32_RS00130 (E4F32_00130) emrD 23613..24797 (-) 1185 WP_032174371.1 multidrug efflux MFS transporter EmrD -
  E4F32_RS23335 ysdE 24879..24953 (+) 75 WP_211180519.1 protein YsdE -
  E4F32_RS00135 (E4F32_00135) tisB 25077..25166 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  E4F32_RS00140 (E4F32_00140) ivbL 25731..25829 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  E4F32_RS00145 (E4F32_00145) ilvB 25935..27623 (+) 1689 WP_000168464.1 acetolactate synthase large subunit -
  E4F32_RS00150 (E4F32_00150) ilvN 27627..27917 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  E4F32_RS00155 (E4F32_00155) letA 27992..28582 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  E4F32_RS00160 (E4F32_00160) uhpB 28582..30084 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  E4F32_RS00165 (E4F32_00165) uhpC 30094..31413 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  E4F32_RS00170 (E4F32_00170) uhpT 31551..32942 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=309666 E4F32_RS00155 WP_000633668.1 27992..28582(+) (letA) [Escherichia coli strain]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=309666 E4F32_RS00155 WP_000633668.1 27992..28582(+) (letA) [Escherichia coli strain]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment