Detailed information NTG0309344

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: DY471_RS21425
• Genome accession: NZ_CP031643
• Coordinates: 4067239..4068033 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain MCCC 1A01412
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4062239..4073033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DY471_RS21405 (DY471_21405)	-	4064042..4064275 (+)	234	WP_001190191.1	DUF2627 domain-containing protein	-
DY471_RS21410 (DY471_21410)	-	4064324..4065052 (-)	729	WP_071728403.1	glycerophosphodiester phosphodiesterase	-
DY471_RS21415 (DY471_21415)	-	4065103..4065249 (+)	147	WP_001247671.1	YycC family protein	-
DY471_RS21420 (DY471_21420)	-	4065417..4066943 (-)	1527	WP_071728404.1	glycosyltransferase family 39 protein	-
DY471_RS21425 (DY471_21425)	spo0A	4067239..4068033 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
DY471_RS21435 (DY471_21435)	spoIVB	4068321..4069619 (-)	1299	WP_002054681.1	SpoIVB peptidase	-
DY471_RS21440 (DY471_21440)	recN	4069738..4071477 (-)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
DY471_RS21445 (DY471_21445)	argR	4071745..4072194 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=309344 DY471_RS21425 WP_003161566.1 4067239..4068033(-) (spo0A) [Bacillus anthracis strain MCCC 1A01412]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=309344 DY471_RS21425 WP_003161566.1 4067239..4068033(-) (spo0A) [Bacillus anthracis strain MCCC 1A01412]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAACAGCCAGATGTACTCG
TATTAGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTTATATT
AAAACCATTTGATATGGAGAATTTAACTAGTCATATTCGTCAAGTGAGCGGTAAAGCGAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAACTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGATACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCTGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818