Detailed information NTG0309176

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZL40_RS07100
• Genome accession: NZ_CP031639
• Coordinates: 1415715..1416716 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS7914
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1410715..1421716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZL40_RS07085 (DZL40_07080)	thrS	1410885..1412828 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZL40_RS07090 (DZL40_07085)	-	1413250..1414584 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZL40_RS07095 (DZL40_07090)	-	1414586..1415584 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZL40_RS07100 (DZL40_07095)	ccpA	1415715..1416716 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZL40_RS07105 (DZL40_07100)	-	1416890..1417975 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZL40_RS07110 (DZL40_07105)	-	1418024..1418689 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZL40_RS07115 (DZL40_07110)	-	1418700..1419077 (+)	378	WP_002985686.1	VOC family protein	-
DZL40_RS07120 (DZL40_07115)	-	1419222..1420148 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZL40_RS07125 (DZL40_07120)	-	1420359..1421042 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=309176 DZL40_RS07100 WP_002985680.1 1415715..1416716(-) (ccpA) [Streptococcus pyogenes strain MGAS7914]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=309176 DZL40_RS07100 WP_002985680.1 1415715..1416716(-) (ccpA) [Streptococcus pyogenes strain MGAS7914]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559