Detailed information NTG0309123

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZM45_RS07010
• Genome accession: NZ_CP031638
• Coordinates: 1410569..1411570 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS8347
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1405569..1416570

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZM45_RS06995 (DZM45_06990)	thrS	1405739..1407682 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZM45_RS07000 (DZM45_06995)	-	1408104..1409438 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZM45_RS07005 (DZM45_07000)	-	1409440..1410438 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZM45_RS07010 (DZM45_07005)	ccpA	1410569..1411570 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZM45_RS07015 (DZM45_07010)	-	1411744..1412829 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZM45_RS07020 (DZM45_07015)	-	1412878..1413543 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZM45_RS07025 (DZM45_07020)	-	1413554..1413931 (+)	378	WP_002985686.1	VOC family protein	-
DZM45_RS07030 (DZM45_07025)	-	1414076..1415002 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZM45_RS07035 (DZM45_07030)	-	1415213..1415896 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=309123 DZM45_RS07010 WP_002985680.1 1410569..1411570(-) (ccpA) [Streptococcus pyogenes strain MGAS8347]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=309123 DZM45_RS07010 WP_002985680.1 1410569..1411570(-) (ccpA) [Streptococcus pyogenes strain MGAS8347]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559